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Page 1
CpG-free plasmids confer reduced inflammation and sustained pulmonary gene expression.
Hyde SC, Pringle IA, Abdullah S, Lawton AE, Davies LA, Varathalingam A, Nunez-Alonso G, Green AM, Bazzani RP, Sumner-Jones SG, Chan M, Li H, Yew NS, Cheng SH, Boyd AC, Davies JC, Griesenbach U, Porteous DJ, Sheppard DN, Munkonge FM, Alton EW, Gill DR. Hyde SC, et al. Among authors: nunez alonso g. Nat Biotechnol. 2008 May;26(5):549-51. doi: 10.1038/nbt1399. Epub 2008 Apr 27. Nat Biotechnol. 2008. PMID: 18438402 Free article. Review.
The use of CpG-free plasmids to mediate persistent gene expression following repeated aerosol delivery of pDNA/PEI complexes.
Davies LA, Hyde SC, Nunez-Alonso G, Bazzani RP, Harding-Smith R, Pringle IA, Lawton AE, Abdullah S, Roberts TC, McCormick D, Sumner-Jones SG, Gill DR. Davies LA, et al. Among authors: nunez alonso g. Biomaterials. 2012 Aug;33(22):5618-27. doi: 10.1016/j.biomaterials.2012.04.019. Epub 2012 May 8. Biomaterials. 2012. PMID: 22575838
CpG-free plasmid expression cassettes for cystic fibrosis gene therapy.
Pringle IA, Hyde SC, Connolly MM, Lawton AE, Xu B, Nunez-Alonso G, Davies LA, Sumner-Jones SG, Gill DR. Pringle IA, et al. Among authors: nunez alonso g. Biomaterials. 2012 Oct;33(28):6833-42. doi: 10.1016/j.biomaterials.2012.06.009. Epub 2012 Jun 22. Biomaterials. 2012. PMID: 22727465
Rapid identification of novel functional promoters for gene therapy.
Pringle IA, Gill DR, Connolly MM, Lawton AE, Hewitt AM, Nunez-Alonso G, Cheng SH, Scheule RK, Davies LA, Hyde SC. Pringle IA, et al. Among authors: nunez alonso g. J Mol Med (Berl). 2012 Dec;90(12):1487-96. doi: 10.1007/s00109-012-0928-6. Epub 2012 Jul 6. J Mol Med (Berl). 2012. PMID: 22767241
BET inhibition as a new strategy for the treatment of gastric cancer.
Montenegro RC, Clark PG, Howarth A, Wan X, Ceroni A, Siejka P, Nunez-Alonso GA, Monteiro O, Rogers C, Gamble V, Burbano R, Brennan PE, Tallant C, Ebner D, Fedorov O, O'Neill E, Knapp S, Dixon D, Müller S. Montenegro RC, et al. Among authors: nunez alonso ga. Oncotarget. 2016 Jul 12;7(28):43997-44012. doi: 10.18632/oncotarget.9766. Oncotarget. 2016. PMID: 27259267 Free PMC article.
Discovery of a Chemical Tool Inhibitor Targeting the Bromodomains of TRIM24 and BRPF.
Bennett J, Fedorov O, Tallant C, Monteiro O, Meier J, Gamble V, Savitsky P, Nunez-Alonso GA, Haendler B, Rogers C, Brennan PE, Müller S, Knapp S. Bennett J, et al. Among authors: nunez alonso ga. J Med Chem. 2016 Feb 25;59(4):1642-7. doi: 10.1021/acs.jmedchem.5b00458. Epub 2015 May 20. J Med Chem. 2016. PMID: 25974391 Free PMC article.