Smith JS - Search Results

1

Interaction of systemically delivered adenovirus vectors with Kupffer cells in mouse liver.

Smith JS, Xu Z, Tian J, Stevenson SC, Byrnes AP. Smith JS, et al. Hum Gene Ther. 2008 May;19(5):547-54. doi: 10.1089/hum.2008.004. Hum Gene Ther. 2008. PMID: 18447633

2

Severe pulmonary pathology after intravenous administration of vectors in cirrhotic rats.

Smith JS, Tian J, Lozier JN, Byrnes AP. Smith JS, et al. Mol Ther. 2004 Jun;9(6):932-41. doi: 10.1016/j.ymthe.2004.03.010. Mol Ther. 2004. PMID: 15194060 Free article.

3

Rapid Kupffer cell death after intravenous injection of adenovirus vectors.

Manickan E, Smith JS, Tian J, Eggerman TL, Lozier JN, Muller J, Byrnes AP. Manickan E, et al. Among authors: smith js. Mol Ther. 2006 Jan;13(1):108-17. doi: 10.1016/j.ymthe.2005.08.007. Epub 2005 Sep 28. Mol Ther. 2006. PMID: 16198149 Free article.

4

A quantitative assay for measuring clearance of adenovirus vectors by Kupffer cells.

Smith JS, Xu Z, Byrnes AP. Smith JS, et al. J Virol Methods. 2008 Jan;147(1):54-60. doi: 10.1016/j.jviromet.2007.08.009. Epub 2007 Sep 11. J Virol Methods. 2008. PMID: 17850893

5

Clearance of adenovirus by Kupffer cells is mediated by scavenger receptors, natural antibodies, and complement.

Xu Z, Tian J, Smith JS, Byrnes AP. Xu Z, et al. Among authors: smith js. J Virol. 2008 Dec;82(23):11705-13. doi: 10.1128/JVI.01320-08. Epub 2008 Sep 24. J Virol. 2008. PMID: 18815305 Free PMC article.

6

Adenovirus activates complement by distinctly different mechanisms in vitro and in vivo: indirect complement activation by virions in vivo.

Tian J, Xu Z, Smith JS, Hofherr SE, Barry MA, Byrnes AP. Tian J, et al. Among authors: smith js. J Virol. 2009 Jun;83(11):5648-58. doi: 10.1128/JVI.00082-09. Epub 2009 Mar 25. J Virol. 2009. PMID: 19321608 Free PMC article.

7

Induction of shock after intravenous injection of adenovirus vectors: a critical role for platelet-activating factor.

Xu Z, Smith JS, Tian J, Byrnes AP. Xu Z, et al. Among authors: smith js. Mol Ther. 2010 Mar;18(3):609-16. doi: 10.1038/mt.2009.279. Epub 2009 Dec 1. Mol Ther. 2010. PMID: 19953082 Free PMC article.

8

Coagulation factor X shields adenovirus type 5 from attack by natural antibodies and complement.

Xu Z, Qiu Q, Tian J, Smith JS, Conenello GM, Morita T, Byrnes AP. Xu Z, et al. Among authors: smith js. Nat Med. 2013 Apr;19(4):452-7. doi: 10.1038/nm.3107. Epub 2013 Mar 24. Nat Med. 2013. PMID: 23524342

9

Unexpected pulmonary uptake of adenovirus vectors in animals with chronic liver disease.

Smith JS, Tian J, Muller J, Byrnes AP. Smith JS, et al. Gene Ther. 2004 Mar;11(5):431-8. doi: 10.1038/sj.gt.3302149. Gene Ther. 2004. PMID: 14973536

10

The role of endosomal escape and mitogen-activated protein kinases in adenoviral activation of the innate immune response.

Smith JS, Xu Z, Tian J, Palmer DJ, Ng P, Byrnes AP. Smith JS, et al. PLoS One. 2011;6(10):e26755. doi: 10.1371/journal.pone.0026755. Epub 2011 Oct 27. PLoS One. 2011. PMID: 22046344 Free PMC article.

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