Miettinen PJ - Search Results

1

Weighing up beta-cell mass in mice and humans: self-renewal, progenitors or stem cells?

Hanley NA, Hanley KP, Miettinen PJ, Otonkoski T. Hanley NA, et al. Among authors: miettinen pj. Mol Cell Endocrinol. 2008 Jun 25;288(1-2):79-85. doi: 10.1016/j.mce.2008.03.001. Epub 2008 Mar 16. Mol Cell Endocrinol. 2008. PMID: 18450368 Review.

2

Insulin-like growth factor-II and transforming growth factor-alpha in developing human fetal pancreatic islets.

Miettinen PJ, Otonkoski T, Voutilainen R. Miettinen PJ, et al. J Endocrinol. 1993 Jul;138(1):127-36. doi: 10.1677/joe.0.1380127. J Endocrinol. 1993. PMID: 7852883

3

Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors.

Miettinen PJ, Huotari M, Koivisto T, Ustinov J, Palgi J, Rasilainen S, Lehtonen E, Keski-Oja J, Otonkoski T. Miettinen PJ, et al. Development. 2000 Jun;127(12):2617-27. doi: 10.1242/dev.127.12.2617. Development. 2000. PMID: 10821760

4

ErbB signaling regulates lineage determination of developing pancreatic islet cells in embryonic organ culture.

Huotari MA, Miettinen PJ, Palgi J, Koivisto T, Ustinov J, Harari D, Yarden Y, Otonkoski T. Huotari MA, et al. Among authors: miettinen pj. Endocrinology. 2002 Nov;143(11):4437-46. doi: 10.1210/en.2002-220382. Endocrinology. 2002. PMID: 12399441

5

Downregulation of EGF receptor signaling in pancreatic islets causes diabetes due to impaired postnatal beta-cell growth.

Miettinen PJ, Ustinov J, Ormio P, Gao R, Palgi J, Hakonen E, Juntti-Berggren L, Berggren PO, Otonkoski T. Miettinen PJ, et al. Diabetes. 2006 Dec;55(12):3299-308. doi: 10.2337/db06-0413. Diabetes. 2006. PMID: 17130473

6

EGF receptor in pancreatic beta-cell mass regulation.

Miettinen P, Ormio P, Hakonen E, Banerjee M, Otonkoski T. Miettinen P, et al. Biochem Soc Trans. 2008 Jun;36(Pt 3):280-5. doi: 10.1042/BST0360280. Biochem Soc Trans. 2008. PMID: 18481942 Review.

7

No effect of the altered peptide ligand NBI-6024 on beta-cell residual function and insulin needs in new-onset type 1 diabetes.

Walter M, Philotheou A, Bonnici F, Ziegler AG, Jimenez R; NBI-6024 Study Group. Walter M, et al. Diabetes Care. 2009 Nov;32(11):2036-40. doi: 10.2337/dc09-0449. Epub 2009 Aug 18. Diabetes Care. 2009. PMID: 19690081 Free PMC article. Clinical Trial.

8

Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation.

Hakonen E, Ustinov J, Mathijs I, Palgi J, Bouwens L, Miettinen PJ, Otonkoski T. Hakonen E, et al. Among authors: miettinen pj. Diabetologia. 2011 Jul;54(7):1735-43. doi: 10.1007/s00125-011-2153-1. Epub 2011 Apr 21. Diabetologia. 2011. PMID: 21509441

9

Extended family history of autoimmune diseases and phenotype and genotype of children with newly diagnosed type 1 diabetes.

Parkkola A, Härkönen T, Ryhänen SJ, Ilonen J, Knip M; Finnish Pediatric Diabetes Register. Parkkola A, et al. Eur J Endocrinol. 2013 Jun 29;169(2):171-8. doi: 10.1530/EJE-13-0089. Print 2013 Aug. Eur J Endocrinol. 2013. PMID: 23698601

10

In vivo activation of the PI3K-Akt pathway in mouse beta cells by the EGFR mutation L858R protects against diabetes.

Hakonen E, Ustinov J, Eizirik DL, Sariola H, Miettinen PJ, Otonkoski T. Hakonen E, et al. Among authors: miettinen pj. Diabetologia. 2014 May;57(5):970-9. doi: 10.1007/s00125-014-3175-2. Epub 2014 Feb 4. Diabetologia. 2014. PMID: 24493201

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