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Page 1
Pharmacological stimulation of type 5 adenylyl cyclase stabilizes heart rate under both microgravity and hypergravity induced by parabolic flight.
Bai Y, Tsunematsu T, Jiao Q, Ohnuki Y, Mototani Y, Shiozawa K, Jin M, Cai W, Jin HL, Fujita T, Ichikawa Y, Suita K, Kurotani R, Yokoyama U, Sato M, Iwatsubo K, Ishikawa Y, Okumura S. Bai Y, et al. Among authors: kurotani r. J Pharmacol Sci. 2012;119(4):381-9. doi: 10.1254/jphs.12102fp. Epub 2012 Jul 31. J Pharmacol Sci. 2012. PMID: 22850613 Free article.
Disruption of type 5 adenylyl cyclase enhances desensitization of cyclic adenosine monophosphate signal and increases Akt signal with chronic catecholamine stress.
Okumura S, Vatner DE, Kurotani R, Bai Y, Gao S, Yuan Z, Iwatsubo K, Ulucan C, Kawabe J, Ghosh K, Vatner SF, Ishikawa Y. Okumura S, et al. Among authors: kurotani r. Circulation. 2007 Oct 16;116(16):1776-83. doi: 10.1161/CIRCULATIONAHA.107.698662. Epub 2007 Sep 24. Circulation. 2007. PMID: 17893275
Caveolin gene transfer improves glucose metabolism in diabetic mice.
Otsu K, Toya Y, Oshikawa J, Kurotani R, Yazawa T, Sato M, Yokoyama U, Umemura S, Minamisawa S, Okumura S, Ishikawa Y. Otsu K, et al. Among authors: kurotani r. Am J Physiol Cell Physiol. 2010 Mar;298(3):C450-6. doi: 10.1152/ajpcell.00077.2009. Epub 2009 Nov 18. Am J Physiol Cell Physiol. 2010. PMID: 19923424 Free article.
Differential regulation of vascular tone and remodeling via stimulation of type 2 and type 6 adenylyl cyclases in the ductus arteriosus.
Yokoyama U, Minamisawa S, Katayama A, Tang T, Suzuki S, Iwatsubo K, Iwasaki S, Kurotani R, Okumura S, Sato M, Yokota S, Hammond HK, Ishikawa Y. Yokoyama U, et al. Among authors: kurotani r. Circ Res. 2010 Jun 25;106(12):1882-92. doi: 10.1161/CIRCRESAHA.109.214924. Epub 2010 Apr 29. Circ Res. 2010. PMID: 20431059 Free PMC article.
Epac activation inhibits IL-6-induced cardiac myocyte dysfunction.
Jin H, Fujita T, Jin M, Kurotani R, Hidaka Y, Cai W, Suita K, Prajapati R, Liang C, Ohnuki Y, Mototani Y, Umemura M, Yokoyama U, Sato M, Okumura S, Ishikawa Y. Jin H, et al. Among authors: kurotani r. J Physiol Sci. 2018 Jan;68(1):77-87. doi: 10.1007/s12576-016-0509-5. Epub 2016 Dec 19. J Physiol Sci. 2018. PMID: 27995459 Free PMC article.
Cardiac overexpression of Epac1 in transgenic mice rescues lipopolysaccharide-induced cardiac dysfunction and inhibits Jak-STAT pathway.
Jin H, Fujita T, Jin M, Kurotani R, Namekata I, Hamaguchi S, Hidaka Y, Cai W, Suita K, Ohnuki Y, Mototani Y, Shiozawa K, Prajapati R, Liang C, Umemura M, Yokoyama U, Sato M, Tanaka H, Okumura S, Ishikawa Y. Jin H, et al. Among authors: kurotani r. J Mol Cell Cardiol. 2017 Jul;108:170-180. doi: 10.1016/j.yjmcc.2017.05.014. Epub 2017 Jun 16. J Mol Cell Cardiol. 2017. PMID: 28629760
54 results