Gray N - Search Results

1

Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility.

Kato N, Sakata T, Breton G, Le Roch KG, Nagle A, Andersen C, Bursulaya B, Henson K, Johnson J, Kumar KA, Marr F, Mason D, McNamara C, Plouffe D, Ramachandran V, Spooner M, Tuntland T, Zhou Y, Peters EC, Chatterjee A, Schultz PG, Ward GE, Gray N, Harper J, Winzeler EA. Kato N, et al. Among authors: gray n. Nat Chem Biol. 2008 Jun;4(6):347-56. doi: 10.1038/nchembio.87. Epub 2008 May 4. Nat Chem Biol. 2008. PMID: 18454143

2

CVT-313, a specific and potent inhibitor of CDK2 that prevents neointimal proliferation.

Brooks EE, Gray NS, Joly A, Kerwar SS, Lum R, Mackman RL, Norman TC, Rosete J, Rowe M, Schow SR, Schultz PG, Wang X, Wick MM, Shiffman D. Brooks EE, et al. Among authors: gray ns. J Biol Chem. 1997 Nov 14;272(46):29207-11. doi: 10.1074/jbc.272.46.29207. J Biol Chem. 1997. PMID: 9360999 Free article.

3

Exploiting chemical libraries, structure, and genomics in the search for kinase inhibitors.

Gray NS, Wodicka L, Thunnissen AM, Norman TC, Kwon S, Espinoza FH, Morgan DO, Barnes G, LeClerc S, Meijer L, Kim SH, Lockhart DJ, Schultz PG. Gray NS, et al. Science. 1998 Jul 24;281(5376):533-8. doi: 10.1126/science.281.5376.533. Science. 1998. PMID: 9677190 Free article.

4

A cyclin-dependent kinase inhibitor inducing cancer cell differentiation: biochemical identification using Xenopus egg extracts.

Rosania GR, Merlie J Jr, Gray N, Chang YT, Schultz PG, Heald R. Rosania GR, et al. Among authors: gray n. Proc Natl Acad Sci U S A. 1999 Apr 27;96(9):4797-802. doi: 10.1073/pnas.96.9.4797. Proc Natl Acad Sci U S A. 1999. PMID: 10220373 Free PMC article.

5

Synthesis and application of functionally diverse 2,6,9-trisubstituted purine libraries as CDK inhibitors.

Chang YT, Gray NS, Rosania GR, Sutherlin DP, Kwon S, Norman TC, Sarohia R, Leost M, Meijer L, Schultz PG. Chang YT, et al. Among authors: gray ns. Chem Biol. 1999 Jun;6(6):361-75. doi: 10.1016/S1074-5521(99)80048-9. Chem Biol. 1999. PMID: 10375538

6

Intracellular targets of cyclin-dependent kinase inhibitors: identification by affinity chromatography using immobilised inhibitors.

Knockaert M, Gray N, Damiens E, Chang YT, Grellier P, Grant K, Fergusson D, Mottram J, Soete M, Dubremetz JF, Le Roch K, Doerig C, Schultz P, Meijer L. Knockaert M, et al. Among authors: gray n. Chem Biol. 2000 Jun;7(6):411-22. doi: 10.1016/s1074-5521(00)00124-1. Chem Biol. 2000. PMID: 10873834

7

A chemical switch for inhibitor-sensitive alleles of any protein kinase.

Bishop AC, Ubersax JA, Petsch DT, Matheos DP, Gray NS, Blethrow J, Shimizu E, Tsien JZ, Schultz PG, Rose MD, Wood JL, Morgan DO, Shokat KM. Bishop AC, et al. Among authors: gray ns. Nature. 2000 Sep 21;407(6802):395-401. doi: 10.1038/35030148. Nature. 2000. PMID: 11014197

8

Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum.

Harmse L, van Zyl R, Gray N, Schultz P, Leclerc S, Meijer L, Doerig C, Havlik I. Harmse L, et al. Among authors: gray n. Biochem Pharmacol. 2001 Aug 1;62(3):341-8. doi: 10.1016/s0006-2952(01)00644-x. Biochem Pharmacol. 2001. PMID: 11434907

9

Design of allele-specific protein methyltransferase inhibitors.

Lin Q, Jiang F, Schultz PG, Gray NS. Lin Q, et al. Among authors: gray ns. J Am Chem Soc. 2001 Nov 28;123(47):11608-13. doi: 10.1021/ja011423j. J Am Chem Soc. 2001. PMID: 11716715

10

Solid-phase synthesis of 2,3,5-trisubstituted indoles.

Wu TY, Ding S, Gray NS, Schultz PG. Wu TY, et al. Among authors: gray ns. Org Lett. 2001 Nov 29;3(24):3827-30. doi: 10.1021/ol016525t. Org Lett. 2001. PMID: 11720546

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