El Kouni MH - Search Results

1

Uridine protects cortical neurons from glucose deprivation-induced death: possible role of uridine phosphorylase.

Choi JW, Shin CY, Choi MS, Yoon SY, Ryu JH, Lee JC, Kim WK, El Kouni MH, Ko KH. Choi JW, et al. Among authors: el kouni mh. J Neurotrauma. 2008 Jun;25(6):695-707. doi: 10.1089/neu.2007.0409. J Neurotrauma. 2008. PMID: 18457515

2

Uridine prevents the glucose deprivation-induced death of immunostimulated astrocytes via the action of uridine phosphorylase.

Choi JW, Yoo BK, Shin CY, Ryu MK, Ryu JH, el Kouni MH, Lee JC, Kim WK, Ko KH. Choi JW, et al. Among authors: el kouni mh. Neurosci Res. 2006 Sep;56(1):111-8. doi: 10.1016/j.neures.2006.06.004. Epub 2006 Jul 12. Neurosci Res. 2006. PMID: 16839635 Free article.

3

Modulation of the pharmacokinetics of endogenous plasma uridine by 5-(phenylthio)acyclouridine, a uridine phosphorylase inhibitor: implications for chemotherapy.

Al Safarjalani ON, Zhou XJ, Naguib FN, Goudgaon NM, Schinazi RF, el Kouni MH. Al Safarjalani ON, et al. Among authors: el kouni mh. Cancer Chemother Pharmacol. 2001 Aug;48(2):145-50. doi: 10.1007/s002800100292. Cancer Chemother Pharmacol. 2001. PMID: 11565561

4

Enhancement of the bioavailability of oral uridine by coadministration of 5-(phenylthio)acyclouridine, a uridine phosphorylase inhibitor: implications for uridine rescue regimens in chemotherapy.

Al Safarjalani ON, Zhou XJ, Naguib FN, Shi J, Schinazi RF, el Kouni MH. Al Safarjalani ON, et al. Among authors: el kouni mh. Cancer Chemother Pharmacol. 2001 Nov;48(5):389-97. doi: 10.1007/s002800100353. Cancer Chemother Pharmacol. 2001. PMID: 11761457

5

Effect of administration of 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase, on the anti-tumor efficacy of 5-fluoro-2'-deoxyuridine against murine colon tumor C26-10.

Ashour OM, Naguib FN, Goudgaon NM, Schinazi RF, el Kouni MH. Ashour OM, et al. Among authors: el kouni mh. Biochem Pharmacol. 2000 Sep 1;60(5):687-92. doi: 10.1016/s0006-2952(00)00375-0. Biochem Pharmacol. 2000. PMID: 10927027

6

Structure-activity relationships of 7-deaza-6-benzylthioinosine analogues as ligands of Toxoplasma gondii adenosine kinase.

Kim YA, Sharon A, Chu CK, Rais RH, Al Safarjalani ON, Naguib FN, el Kouni MH. Kim YA, et al. Among authors: el kouni mh. J Med Chem. 2008 Jul 10;51(13):3934-45. doi: 10.1021/jm800201s. Epub 2008 Jun 19. J Med Chem. 2008. PMID: 18563892

7

Modulation of plasma uridine concentration by 5-(phenylselenenyl)acyclouridine, an inhibitor of uridine phosphorylase: relevance to chemotherapy.

Ashour OM, Al Safarjalani ON, Naguib FN, Goudgaon NM, Schinazi RF, el Kouni MH. Ashour OM, et al. Among authors: el kouni mh. Cancer Chemother Pharmacol. 2000;45(5):351-61. doi: 10.1007/s002800051002. Cancer Chemother Pharmacol. 2000. PMID: 10803917

8

Modulation of 5-fluorouracil host-toxicity and chemotherapeutic efficacy against human colon tumors by 5-(Phenylthio)acyclouridine, a uridine phosphorylase inhibitor.

Al Safarjalani ON, Rais R, Shi J, Schinazi RF, Naguib FN, el Kouni MH. Al Safarjalani ON, et al. Among authors: el kouni mh. Cancer Chemother Pharmacol. 2006 Nov;58(5):692-8. doi: 10.1007/s00280-006-0213-x. Epub 2006 Mar 10. Cancer Chemother Pharmacol. 2006. PMID: 16528530

9

Uridine phosphorylase from Schistosoma mansoni.

el Kouni MH, Naguib FN, Niedzwicki JG, Iltzsch MH, Cha S. el Kouni MH, et al. J Biol Chem. 1988 May 5;263(13):6081-6. J Biol Chem. 1988. PMID: 3360774 Free article.

10

Potent combination therapy for human breast tumors with high doses of 5-fluorouracil: remission and lack of host toxicity.

Al Safarjalani ON, Rais R, Naguib FN, el Kouni MH. Al Safarjalani ON, et al. Among authors: el kouni mh. Cancer Chemother Pharmacol. 2012 Jun;69(6):1449-55. doi: 10.1007/s00280-012-1842-x. Epub 2012 Feb 29. Cancer Chemother Pharmacol. 2012. PMID: 22373605

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