Mackinnon A - Search Results

1

Targeting growth factors in lung cancer.

Hodkinson PS, Mackinnon A, Sethi T. Hodkinson PS, et al. Among authors: mackinnon a. Chest. 2008 May;133(5):1209-16. doi: 10.1378/chest.07-2680. Chest. 2008. PMID: 18460519 Review.

2

Targeting V1A-vasopressin receptors with [Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) identifies a strategy to develop novel anti-cancer therapies.

MacKinnon AC, Tufail-Hanif U, Wheatley M, Rossi AG, Haslett C, Seckl M, Sethi T. MacKinnon AC, et al. Br J Pharmacol. 2009 Jan;156(1):36-47. doi: 10.1111/j.1476-5381.2008.00003.x. Br J Pharmacol. 2009. PMID: 19133990 Free PMC article.

3

The molecular and cellular biology of lung cancer: identifying novel therapeutic strategies.

MacKinnon AC, Kopatz J, Sethi T. MacKinnon AC, et al. Br Med Bull. 2010;95:47-61. doi: 10.1093/bmb/ldq023. Epub 2010 Jul 19. Br Med Bull. 2010. PMID: 20643690 Free article. Review.

4

ECM overrides DNA damage-induced cell cycle arrest and apoptosis in small-cell lung cancer cells through beta1 integrin-dependent activation of PI3-kinase.

Hodkinson PS, Elliott T, Wong WS, Rintoul RC, Mackinnon AC, Haslett C, Sethi T. Hodkinson PS, et al. Among authors: mackinnon ac. Cell Death Differ. 2006 Oct;13(10):1776-88. doi: 10.1038/sj.cdd.4401849. Epub 2006 Jan 27. Cell Death Differ. 2006. PMID: 16410797

5

Extracellular matrix regulation of drug resistance in small-cell lung cancer.

Hodkinson PS, Mackinnon AC, Sethi T. Hodkinson PS, et al. Among authors: mackinnon ac. Int J Radiat Biol. 2007 Nov-Dec;83(11-12):733-41. doi: 10.1080/09553000701570204. Int J Radiat Biol. 2007. PMID: 17852559 Review.

6

[D-Arg6, D-Trp7,9, NmePhe8]-substance P (6-11) activates JNK and induces apoptosis in small cell lung cancer cells via an oxidant-dependent mechanism.

MacKinnon A, Sethi T. MacKinnon A, et al. Methods Mol Med. 2003;74:299-307. doi: 10.1385/1-59259-323-2:299. Methods Mol Med. 2003. PMID: 12415704 No abstract available.

7

Cross-linking CD98 promotes integrin-like signaling and anchorage-independent growth.

Rintoul RC, Buttery RC, Mackinnon AC, Wong WS, Mosher D, Haslett C, Sethi T. Rintoul RC, et al. Mol Biol Cell. 2002 Aug;13(8):2841-52. doi: 10.1091/mbc.01-11-0530. Mol Biol Cell. 2002. PMID: 12181350 Free PMC article.

8

Phospholipase C epsilon suppresses integrin activation.

Lad Y, McHugh B, Hodkinson PS, Mackinnon AC, Haslett C, Ginsberg MH, Sethi T. Lad Y, et al. J Biol Chem. 2006 Oct 6;281(40):29501-12. doi: 10.1074/jbc.M513471200. Epub 2006 Aug 8. J Biol Chem. 2006. PMID: 16895916 Free article.

9

Critical role of c-jun (NH2) terminal kinase in paracetamol- induced acute liver failure.

Henderson NC, Pollock KJ, Frew J, Mackinnon AC, Flavell RA, Davis RJ, Sethi T, Simpson KJ. Henderson NC, et al. Among authors: mackinnon ac. Gut. 2007 Jul;56(7):982-90. doi: 10.1136/gut.2006.104372. Epub 2006 Dec 21. Gut. 2007. PMID: 17185352 Free PMC article.

10

Mammalian NOTCH-1 activates beta1 integrins via the small GTPase R-Ras.

Hodkinson PS, Elliott PA, Lad Y, McHugh BJ, MacKinnon AC, Haslett C, Sethi T. Hodkinson PS, et al. Among authors: mackinnon ac. J Biol Chem. 2007 Sep 28;282(39):28991-29001. doi: 10.1074/jbc.M703601200. Epub 2007 Jul 30. J Biol Chem. 2007. PMID: 17664272 Free article.

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