Sazani P - Search Results

1

An endogenous TNF-alpha antagonist induced by splice-switching oligonucleotides reduces inflammation in hepatitis and arthritis mouse models.

Graziewicz MA, Tarrant TK, Buckley B, Roberts J, Fulton L, Hansen H, Ørum H, Kole R, Sazani P. Graziewicz MA, et al. Among authors: sazani p. Mol Ther. 2008 Jul;16(7):1316-22. doi: 10.1038/mt.2008.85. Epub 2008 May 6. Mol Ther. 2008. PMID: 18461057 Free PMC article.

2

Efficient and persistent splice switching by systemically delivered LNA oligonucleotides in mice.

Roberts J, Palma E, Sazani P, Ørum H, Cho M, Kole R. Roberts J, et al. Among authors: sazani p. Mol Ther. 2006 Oct;14(4):471-5. doi: 10.1016/j.ymthe.2006.05.017. Epub 2006 Jul 18. Mol Ther. 2006. PMID: 16854630 Free article.

3

Sustained dystrophin expression induced by peptide-conjugated morpholino oligomers in the muscles of mdx mice.

Jearawiriyapaisarn N, Moulton HM, Buckley B, Roberts J, Sazani P, Fucharoen S, Iversen PL, Kole R. Jearawiriyapaisarn N, et al. Among authors: sazani p. Mol Ther. 2008 Sep;16(9):1624-9. doi: 10.1038/mt.2008.120. Epub 2008 Jun 10. Mol Ther. 2008. PMID: 18545222 Free PMC article.

4

An Endogenous TNF-α Antagonist Induced by Splice-switching Oligonucleotides Reduces Inflammation in Hepatitis and Arthritis Mouse Models.

Graziewicz MA, Tarrant TK, Buckley B, Roberts J, Fulton L, Hansen H, Ørum H, Kole R, Sazani P. Graziewicz MA, et al. Among authors: sazani p. Mol Ther. 2008 Jul;16(7):1316-1322. doi: 10.1038/mt.2008.85. Epub 2016 Dec 8. Mol Ther. 2008. PMID: 28178484

5

Therapeutic potential of antisense oligonucleotides as modulators of alternative splicing.

Sazani P, Kole R. Sazani P, et al. J Clin Invest. 2003 Aug;112(4):481-6. doi: 10.1172/JCI19547. J Clin Invest. 2003. PMID: 12925686 Free PMC article. Review.

6

Modification of HER2 pre-mRNA alternative splicing and its effects on breast cancer cells.

Wan J, Sazani P, Kole R. Wan J, et al. Among authors: sazani p. Int J Cancer. 2009 Feb 15;124(4):772-7. doi: 10.1002/ijc.24052. Int J Cancer. 2009. PMID: 19035464 Free PMC article.

7

Antisense effects in the cell nucleus: modification of splicing.

Kole R, Sazani P. Kole R, et al. Among authors: sazani p. Curr Opin Mol Ther. 2001 Jun;3(3):229-34. Curr Opin Mol Ther. 2001. PMID: 11497345 Review.

8

Short-term and long-term modulation of gene expression by antisense therapeutics.

Sazani P, Vacek MM, Kole R. Sazani P, et al. Curr Opin Biotechnol. 2002 Oct;13(5):468-72. doi: 10.1016/s0958-1669(02)00366-x. Curr Opin Biotechnol. 2002. PMID: 12459339 Review.

9

Oligonucleotide therapeutics in cancer.

Wan J, Bauman JA, Graziewicz MA, Sazani P, Kole R. Wan J, et al. Among authors: sazani p. Cancer Treat Res. 2013;158:213-33. doi: 10.1007/978-3-642-31659-3_9. Cancer Treat Res. 2013. PMID: 24222360

10

Modification of alternative splicing by antisense oligonucleotides as a potential chemotherapy for cancer and other diseases.

Mercatante DR, Sazani P, Kole R. Mercatante DR, et al. Among authors: sazani p. Curr Cancer Drug Targets. 2001 Nov;1(3):211-30. doi: 10.2174/1568009013334124. Curr Cancer Drug Targets. 2001. PMID: 12188880 Review.

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