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Page 1
Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors.
Cumming JN, Le TX, Babu S, Carroll C, Chen X, Favreau L, Gaspari P, Guo T, Hobbs DW, Huang Y, Iserloh U, Kennedy ME, Kuvelkar R, Li G, Lowrie J, McHugh NA, Ozgur L, Pan J, Parker EM, Saionz K, Stamford AW, Strickland C, Tadesse D, Voigt J, Wang L, Wu Y, Zhang L, Zhang Q. Cumming JN, et al. Among authors: babu s. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3236-41. doi: 10.1016/j.bmcl.2008.04.050. Epub 2008 Apr 25. Bioorg Med Chem Lett. 2008. PMID: 18468890
Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization.
Cumming J, Babu S, Huang Y, Carrol C, Chen X, Favreau L, Greenlee W, Guo T, Kennedy M, Kuvelkar R, Le T, Li G, McHugh N, Orth P, Ozgur L, Parker E, Saionz K, Stamford A, Strickland C, Tadesse D, Voigt J, Zhang L, Zhang Q. Cumming J, et al. Among authors: babu s. Bioorg Med Chem Lett. 2010 May 1;20(9):2837-42. doi: 10.1016/j.bmcl.2010.03.050. Epub 2010 Mar 12. Bioorg Med Chem Lett. 2010. PMID: 20347593
Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor that Affords Robust CNS Aβ Reduction.
Stamford AW, Scott JD, Li SW, Babu S, Tadesse D, Hunter R, Wu Y, Misiaszek J, Cumming JN, Gilbert EJ, Huang C, McKittrick BA, Hong L, Guo T, Zhu Z, Strickland C, Orth P, Voigt JH, Kennedy ME, Chen X, Kuvelkar R, Hodgson R, Hyde LA, Cox K, Favreau L, Parker EM, Greenlee WJ. Stamford AW, et al. Among authors: babu s. ACS Med Chem Lett. 2012 Nov 8;3(11):897-902. doi: 10.1021/ml3001165. Epub 2012 Jul 12. ACS Med Chem Lett. 2012. PMID: 23412139 Free PMC article.
Highly efficient and versatile synthesis of libraries of constrained beta-strand mimetics.
Ogbu CO, Qabar MN, Boatman PD, Urban J, Meara JP, Ferguson MD, Tulinsky J, Lum C, Babu S, Blaskovich MA, Nakanishi H, Ruan F, Cao B, Minarik R, Little T, Nelson S, Nguyen M, Gall A, Kahn M. Ogbu CO, et al. Among authors: babu s. Bioorg Med Chem Lett. 1998 Sep 8;8(17):2321-6. doi: 10.1016/s0960-894x(98)00420-x. Bioorg Med Chem Lett. 1998. PMID: 9873535
3D-Printable Elastomers for Real-Time Autonomous Self-Healing in Soft Devices.
Beckett JG, Thrasher CJ, Michonski J, Drexler RM, Babu S, Cox AM, Windham BJ, Yu Z, Auguste AD, Shetty A, Osborn TH, Lowe RL, Sowards LA, Crouse CA. Beckett JG, et al. Among authors: babu s. ACS Mater Lett. 2024 Dec 3;7(1):123-132. doi: 10.1021/acsmaterialslett.4c01358. eCollection 2025 Jan 6. ACS Mater Lett. 2024. PMID: 39790739 Free PMC article.
Phase 2 Open-Label Study of Sacituzumab Govitecan as Second-Line Therapy in Patients With Extensive-Stage Small Cell Lung Cancer: Results From TROPiCS-03.
Dowlati A, Chiang AC, Cervantes A, Babu S, Hamilton E, Wong SF, Tazbirkova A, Sullivan IG, van Marcke C, Italiano A, Patel J, Mekan S, Wu T, Waqar SN. Dowlati A, et al. Among authors: babu s. J Thorac Oncol. 2025 Jan 2:S1556-0864(24)02549-8. doi: 10.1016/j.jtho.2024.12.028. Online ahead of print. J Thorac Oncol. 2025. PMID: 39755168
1,749 results