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Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors.
Cumming JN, Le TX, Babu S, Carroll C, Chen X, Favreau L, Gaspari P, Guo T, Hobbs DW, Huang Y, Iserloh U, Kennedy ME, Kuvelkar R, Li G, Lowrie J, McHugh NA, Ozgur L, Pan J, Parker EM, Saionz K, Stamford AW, Strickland C, Tadesse D, Voigt J, Wang L, Wu Y, Zhang L, Zhang Q. Cumming JN, et al. Among authors: guo t. Bioorg Med Chem Lett. 2008 Jun 1;18(11):3236-41. doi: 10.1016/j.bmcl.2008.04.050. Epub 2008 Apr 25. Bioorg Med Chem Lett. 2008. PMID: 18468890
Library design concepts and implementation strategies.
Hobbs DW, Guo T. Hobbs DW, et al. Among authors: guo t. J Recept Signal Transduct Res. 2001 Nov;21(4):311-56. doi: 10.1081/rrs-100107922. J Recept Signal Transduct Res. 2001. PMID: 11789688 Review. No abstract available.
2-(Aminomethyl)-benzamide-based glycine transporter type-2 inhibitors.
Ho KK, Appell KC, Baldwin JJ, Bohnstedt AC, Dong G, Guo T, Horlick R, Islam KR, Kultgen SG, Masterson CM, McDonald E, McMillan K, Morphy JR, Rankovic Z, Sundaram H, Webb M. Ho KK, et al. Among authors: guo t. Bioorg Med Chem Lett. 2004 Jan 19;14(2):545-8. doi: 10.1016/j.bmcl.2003.09.080. Bioorg Med Chem Lett. 2004. PMID: 14698200
6,145 results