Altered -3 substrate specificity of Escherichia coli signal peptidase 1 mutants as revealed by screening a combinatorial peptide library.
Ekici OD, Karla A, Paetzel M, Lively MO, Pei D, Dalbey RE.
Ekici OD, et al. Among authors: paetzel m.
J Biol Chem. 2007 Jan 5;282(1):417-25. doi: 10.1074/jbc.M608779200. Epub 2006 Oct 31.
J Biol Chem. 2007.
PMID: 17077081
Free article.
Previously, we have reported that certain alterations of the Ile-144 and Ile-86 residues in Escherichia coli signal peptidase I (SPase) can change the specificity such that signal peptidase is able to cleave pro-OmpA nuclease A in vitro after phenylalanine or asparagine residues …
Previously, we have reported that certain alterations of the Ile-144 and Ile-86 residues in Escherichia coli signal peptidase I (SPase) can …