Hruby DE - Search Results

1

Evaluation of orally delivered ST-246 as postexposure prophylactic and antiviral therapeutic in an aerosolized rabbitpox rabbit model.

Nalca A, Hatkin JM, Garza NL, Nichols DK, Norris SW, Hruby DE, Jordan R. Nalca A, et al. Among authors: hruby de. Antiviral Res. 2008 Aug;79(2):121-7. doi: 10.1016/j.antiviral.2008.03.005. Epub 2008 Apr 23. Antiviral Res. 2008. PMID: 18479761

2

Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246.

Huggins J, Goff A, Hensley L, Mucker E, Shamblin J, Wlazlowski C, Johnson W, Chapman J, Larsen T, Twenhafel N, Karem K, Damon IK, Byrd CM, Bolken TC, Jordan R, Hruby D. Huggins J, et al. Antimicrob Agents Chemother. 2009 Jun;53(6):2620-5. doi: 10.1128/AAC.00021-09. Epub 2009 Apr 6. Antimicrob Agents Chemother. 2009. PMID: 19349521 Free PMC article.

3

Evaluation of disease and viral biomarkers as triggers for therapeutic intervention in respiratory mousepox - an animal model of smallpox.

Parker S, Chen NG, Foster S, Hartzler H, Hembrador E, Hruby D, Jordan R, Lanier R, Painter G, Painter W, Sagartz JE, Schriewer J, Mark Buller R. Parker S, et al. Antiviral Res. 2012 Apr;94(1):44-53. doi: 10.1016/j.antiviral.2012.02.005. Epub 2012 Feb 18. Antiviral Res. 2012. PMID: 22381921 Free PMC article.

4

Evaluation of Lassa antiviral compound ST-193 in a guinea pig model.

Cashman KA, Smith MA, Twenhafel NA, Larson RA, Jones KF, Allen RD 3rd, Dai D, Chinsangaram J, Bolken TC, Hruby DE, Amberg SM, Hensley LE, Guttieri MC. Cashman KA, et al. Among authors: hruby de. Antiviral Res. 2011 Apr;90(1):70-9. doi: 10.1016/j.antiviral.2011.02.012. Epub 2011 Mar 1. Antiviral Res. 2011. PMID: 21371508 Free PMC article.

5

Increased susceptibility of Cantagalo virus to the antiviral effect of ST-246®.

Santos-Fernandes É, Beltrame CO, Byrd CM, Cardwell KB, Schnellrath LC, Medaglia ML, Hruby DE, Jordan R, Damaso CR. Santos-Fernandes É, et al. Among authors: hruby de. Antiviral Res. 2013 Mar;97(3):301-11. doi: 10.1016/j.antiviral.2012.11.010. Epub 2012 Dec 17. Antiviral Res. 2013. PMID: 23257396 Free article.

6

Smallpox antiviral drug development: satisfying the animal efficacy rule.

Jordan R, Hruby D. Jordan R, et al. Expert Rev Anti Infect Ther. 2006 Apr;4(2):277-89. doi: 10.1586/14787210.4.2.277. Expert Rev Anti Infect Ther. 2006. PMID: 16597208 Free PMC article. Review.

7

Deletion of the vaccinia virus F13L gene results in a highly attenuated virus that mounts a protective immune response against subsequent vaccinia virus challenge.

Vliegen I, Yang G, Hruby D, Jordan R, Neyts J. Vliegen I, et al. Antiviral Res. 2012 Jan;93(1):160-6. doi: 10.1016/j.antiviral.2011.11.010. Epub 2011 Nov 25. Antiviral Res. 2012. PMID: 22138484

8

Activity of the anti-orthopoxvirus compound ST-246 against vaccinia, cowpox and camelpox viruses in cell monolayers and organotypic raft cultures.

Duraffour S, Snoeck R, de Vos R, van Den Oord JJ, Crance JM, Garin D, Hruby DE, Jordan R, De Clercq E, Andrei G. Duraffour S, et al. Among authors: de vos r, de clercq e, hruby de. Antivir Ther. 2007;12(8):1205-16. Antivir Ther. 2007. PMID: 18240860

9

Effective antiviral treatment of systemic orthopoxvirus disease: ST-246 treatment of prairie dogs infected with monkeypox virus.

Smith SK, Self J, Weiss S, Carroll D, Braden Z, Regnery RL, Davidson W, Jordan R, Hruby DE, Damon IK. Smith SK, et al. Among authors: hruby de. J Virol. 2011 Sep;85(17):9176-87. doi: 10.1128/JVI.02173-10. Epub 2011 Jun 22. J Virol. 2011. PMID: 21697474 Free PMC article.

10

Immune responses to the smallpox vaccine given in combination with ST-246, a small-molecule inhibitor of poxvirus dissemination.

Grosenbach DW, Jordan R, King DS, Berhanu A, Warren TK, Kirkwood-Watts DL, Tyavanagimatt S, Tan Y, Wilson RL, Jones KF, Hruby DE. Grosenbach DW, et al. Among authors: hruby de. Vaccine. 2008 Feb 13;26(7):933-46. doi: 10.1016/j.vaccine.2007.11.095. Epub 2007 Dec 26. Vaccine. 2008. PMID: 18226434 Free PMC article.

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