Settleman J - Search Results

1

p190A RhoGAP is a glycogen synthase kinase-3-beta substrate required for polarized cell migration.

Jiang W, Betson M, Mulloy R, Foster R, Lévay M, Ligeti E, Settleman J. Jiang W, et al. Among authors: settleman j. J Biol Chem. 2008 Jul 25;283(30):20978-88. doi: 10.1074/jbc.M802588200. Epub 2008 May 23. J Biol Chem. 2008. PMID: 18502760 Free PMC article.

2

A rho-binding protein kinase C-like activity is required for the function of protein kinase N in Drosophila development.

Betson M, Settleman J. Betson M, et al. Among authors: settleman j. Genetics. 2007 Aug;176(4):2201-12. doi: 10.1534/genetics.107.072967. Epub 2007 May 16. Genetics. 2007. PMID: 17507675 Free PMC article.

3

Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis.

Sordella R, Jiang W, Chen GC, Curto M, Settleman J. Sordella R, et al. Among authors: settleman j. Cell. 2003 Apr 18;113(2):147-58. doi: 10.1016/s0092-8674(03)00271-x. Cell. 2003. PMID: 12705864 Free article.

4

An FF domain-dependent protein interaction mediates a signaling pathway for growth factor-induced gene expression.

Jiang W, Sordella R, Chen GC, Hakre S, Roy AL, Settleman J. Jiang W, et al. Among authors: settleman j. Mol Cell. 2005 Jan 7;17(1):23-35. doi: 10.1016/j.molcel.2004.11.024. Mol Cell. 2005. PMID: 15629714 Free article.

5

Drosophila Rho-kinase (DRok) is required for tissue morphogenesis in diverse compartments of the egg chamber during oogenesis.

Verdier V, Johndrow JE, Betson M, Chen GC, Hughes DA, Parkhurst SM, Settleman J. Verdier V, et al. Among authors: settleman j. Dev Biol. 2006 Sep 15;297(2):417-32. doi: 10.1016/j.ydbio.2006.05.016. Epub 2006 May 19. Dev Biol. 2006. PMID: 16887114 Free PMC article.

6

Regulation of the substrate preference of p190RhoGAP by protein kinase C-mediated phosphorylation of a phospholipid binding site.

Lévay M, Settleman J, Ligeti E. Lévay M, et al. Among authors: settleman j. Biochemistry. 2009 Sep 15;48(36):8615-23. doi: 10.1021/bi900667y. Biochemistry. 2009. PMID: 19673492 Free PMC article.

7

Phospholipids can switch the GTPase substrate preference of a GTPase-activating protein.

Ligeti E, Dagher MC, Hernandez SE, Koleske AJ, Settleman J. Ligeti E, et al. Among authors: settleman j. J Biol Chem. 2004 Feb 13;279(7):5055-8. doi: 10.1074/jbc.C300547200. Epub 2003 Dec 29. J Biol Chem. 2004. PMID: 14699145 Free article.

8

p190 RhoGAP, the major RasGAP-associated protein, binds GTP directly.

Foster R, Hu KQ, Shaywitz DA, Settleman J. Foster R, et al. Among authors: settleman j. Mol Cell Biol. 1994 Nov;14(11):7173-81. doi: 10.1128/mcb.14.11.7173-7181.1994. Mol Cell Biol. 1994. PMID: 7935432 Free PMC article.

9

Epidermal growth factor receptor mutants from human lung cancers exhibit enhanced catalytic activity and increased sensitivity to gefitinib.

Mulloy R, Ferrand A, Kim Y, Sordella R, Bell DW, Haber DA, Anderson KS, Settleman J. Mulloy R, et al. Among authors: settleman j. Cancer Res. 2007 Mar 1;67(5):2325-30. doi: 10.1158/0008-5472.CAN-06-4293. Cancer Res. 2007. PMID: 17332364

10

Regulation of RhoGAP specificity by phospholipids and prenylation.

Ligeti E, Settleman J. Ligeti E, et al. Among authors: settleman j. Methods Enzymol. 2006;406:104-17. doi: 10.1016/S0076-6879(06)06009-5. Methods Enzymol. 2006. PMID: 16472653

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