Yasuda K - Search Results

1

A comprehensive in vitro and in silico analysis of antibiotics that activate pregnane X receptor and induce CYP3A4 in liver and intestine.

Yasuda K, Ranade A, Venkataramanan R, Strom S, Chupka J, Ekins S, Schuetz E, Bachmann K. Yasuda K, et al. Drug Metab Dispos. 2008 Aug;36(8):1689-97. doi: 10.1124/dmd.108.020701. Epub 2008 May 27. Drug Metab Dispos. 2008. PMID: 18505790 Free PMC article.

2

Development of a real-time in vivo transcription assay: application reveals pregnane X receptor-mediated induction of CYP3A4 by cancer chemotherapeutic agents.

Schuetz E, Lan L, Yasuda K, Kim R, Kocarek TA, Schuetz J, Strom S. Schuetz E, et al. Among authors: yasuda k. Mol Pharmacol. 2002 Sep;62(3):439-45. doi: 10.1124/mol.62.3.439. Mol Pharmacol. 2002. PMID: 12181418

3

The major human pregnane X receptor (PXR) splice variant, PXR.2, exhibits significantly diminished ligand-activated transcriptional regulation.

Lin YS, Yasuda K, Assem M, Cline C, Barber J, Li CW, Kholodovych V, Ai N, Chen JD, Welsh WJ, Ekins S, Schuetz EG. Lin YS, et al. Among authors: yasuda k. Drug Metab Dispos. 2009 Jun;37(6):1295-304. doi: 10.1124/dmd.108.025213. Epub 2009 Feb 27. Drug Metab Dispos. 2009. PMID: 19251824 Free PMC article.

4

Genetic variation in aldo-keto reductase 1D1 (AKR1D1) affects the expression and activity of multiple cytochrome P450s.

Chaudhry AS, Thirumaran RK, Yasuda K, Yang X, Fan Y, Strom SC, Schuetz EG. Chaudhry AS, et al. Among authors: yasuda k. Drug Metab Dispos. 2013 Aug;41(8):1538-47. doi: 10.1124/dmd.113.051672. Epub 2013 May 23. Drug Metab Dispos. 2013. PMID: 23704699 Free PMC article.

5

Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice.

Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD. Assem M, et al. Among authors: yasuda k. J Biol Chem. 2004 May 21;279(21):22250-7. doi: 10.1074/jbc.M314111200. Epub 2004 Mar 5. J Biol Chem. 2004. PMID: 15004017 Free article.

6

PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators.

Lamba V, Yasuda K, Lamba JK, Assem M, Davila J, Strom S, Schuetz EG. Lamba V, et al. Among authors: yasuda k. Toxicol Appl Pharmacol. 2004 Sep 15;199(3):251-65. doi: 10.1016/j.taap.2003.12.027. Toxicol Appl Pharmacol. 2004. PMID: 15364541

7

Role of the nuclear receptor pregnane X receptor in acetaminophen hepatotoxicity.

Wolf KK, Wood SG, Hunt JA, Walton-Strong BW, Yasuda K, Lan L, Duan SX, Hao Q, Wrighton SA, Jeffery EH, Evans RM, Szakacs JG, von Moltke LL, Greenblatt DJ, Court MH, Schuetz EG, Sinclair PR, Sinclair JF. Wolf KK, et al. Among authors: yasuda k. Drug Metab Dispos. 2005 Dec;33(12):1827-36. doi: 10.1124/dmd.105.005256. Epub 2005 Sep 1. Drug Metab Dispos. 2005. PMID: 16141365

8

Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier.

Yasuda K, Cline C, Vogel P, Onciu M, Fatima S, Sorrentino BP, Thirumaran RK, Ekins S, Urade Y, Fujimori K, Schuetz EG. Yasuda K, et al. Drug Metab Dispos. 2013 Apr;41(4):923-31. doi: 10.1124/dmd.112.050344. Epub 2013 Jan 8. Drug Metab Dispos. 2013. PMID: 23298861 Free PMC article.

9

In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice.

Yasuda K, Cline C, Lin YS, Scheib R, Ganguly S, Thirumaran RK, Chaudhry A, Kim RB, Schuetz EG. Yasuda K, et al. Drug Metab Dispos. 2015 Nov;43(11):1646-54. doi: 10.1124/dmd.115.065078. Epub 2015 Aug 17. Drug Metab Dispos. 2015. PMID: 26281846 Free PMC article.

10

Pheophorbide A: Fluorescent Bcrp Substrate to Measure Oral Drug-Drug Interactions in Real-Time In Vivo.

Yasuda K, Ganguly S, Schuetz EG. Yasuda K, et al. Drug Metab Dispos. 2018 Nov;46(11):1725-1733. doi: 10.1124/dmd.118.083584. Epub 2018 Aug 15. Drug Metab Dispos. 2018. PMID: 30111622 Free PMC article.

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