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The inhibin B response in male rats treated with two drug candidates.
Chapin RE, Alvey JD, Goldstein RA, Dokmanovich MG, Reagan WJ, Johnson K, Geoly FJ. Chapin RE, et al. Among authors: reagan wj. Birth Defects Res B Dev Reprod Toxicol. 2013 Feb;98(1):54-62. doi: 10.1002/bdrb.21040. Epub 2013 Jan 24. Birth Defects Res B Dev Reprod Toxicol. 2013. PMID: 23348891
Liver Microvascular Injury and Thrombocytopenia of Antibody-Calicheamicin Conjugates in Cynomolgus Monkeys-Mechanism and Monitoring.
Guffroy M, Falahatpisheh H, Biddle K, Kreeger J, Obert L, Walters K, Goldstein R, Boucher G, Coskran T, Reagan W, Sullivan D, Huang C, Sokolowski S, Giovanelli R, Gerber HP, Finkelstein M, Khan N. Guffroy M, et al. Clin Cancer Res. 2017 Apr 1;23(7):1760-1770. doi: 10.1158/1078-0432.CCR-16-0939. Epub 2016 Sep 28. Clin Cancer Res. 2017. PMID: 27683177
Summary of the HESI consortium studies exploring circulating inhibin B as a potential biomarker of testis damage in the rat.
Chapin R, Weinbauer G, Thibodeau MS, Sonee M, Saldutti LP, Reagan WJ, Potter D, Moffit JS, Laffan S, Kim JH, Goldstein RA, Erdos Z, Enright BP, Coulson M, Breslin WJ. Chapin R, et al. Among authors: reagan wj. Birth Defects Res B Dev Reprod Toxicol. 2013 Feb;98(1):110-8. doi: 10.1002/bdrb.21041. Epub 2013 Jan 30. Birth Defects Res B Dev Reprod Toxicol. 2013. PMID: 23364877
The use of emerging safety biomarkers in nonclinical and clinical safety assessment - The current and future state: An IQ DruSafe industry survey.
Zabka TS, Burkhardt J, Reagan WJ, Gautier JC, Glaab WE, Guffroy M, Harding J, Brees D, McDuffie E, Ramaiah L, Schultze AE, Smith JD, Wolfreys A, Dalmas DA. Zabka TS, et al. Among authors: reagan wj. Regul Toxicol Pharmacol. 2021 Mar;120:104857. doi: 10.1016/j.yrtph.2020.104857. Epub 2020 Dec 31. Regul Toxicol Pharmacol. 2021. PMID: 33387566 Free article.
53 results