d'Oiron R - Search Results

1

Mild/moderate haemophilia A: new insights into molecular mechanisms and inhibitor development.

d'Oiron R, Pipe SW, Jacquemin M. d'Oiron R, et al. Haemophilia. 2008 Jul;14 Suppl 3:138-46. doi: 10.1111/j.1365-2516.2008.01730.x. Haemophilia. 2008. PMID: 18510534 Free article. Review.

2

A human antibody directed to the factor VIII C1 domain inhibits factor VIII cofactor activity and binding to von Willebrand factor.

Jacquemin M, Benhida A, Peerlinck K, Desqueper B, Vander Elst L, Lavend'homme R, d'Oiron R, Schwaab R, Bakkus M, Thielemans K, Gilles JG, Vermylen J, Saint-Remy JM. Jacquemin M, et al. Blood. 2000 Jan 1;95(1):156-63. Blood. 2000. PMID: 10607698 Free article.

3

A novel cause of mild/moderate hemophilia A: mutations scattered in the factor VIII C1 domain reduce factor VIII binding to von Willebrand factor.

Jacquemin M, Lavend'homme R, Benhida A, Vanzieleghem B, d'Oiron R, Lavergne JM, Brackmann HH, Schwaab R, VandenDriessche T, Chuah MK, Hoylaerts M, Gilles JG, Peerlinck K, Vermylen J, Saint-Remy JM. Jacquemin M, et al. Blood. 2000 Aug 1;96(3):958-65. Blood. 2000. PMID: 10910910 Free article.

4

Molecular mechanisms of mild and moderate hemophilia A.

Jacquemin M, De Maeyer M, D'Oiron R, Lavend'Homme R, Peerlinck K, Saint-Remy JM. Jacquemin M, et al. J Thromb Haemost. 2003 Mar;1(3):456-63. doi: 10.1046/j.1538-7836.2003.00088.x. J Thromb Haemost. 2003. PMID: 12871450 Free article. Review.

5

Deletion of alanine 2201 in the FVIII C2 domain results in mild hemophilia A by impairing FVIII binding to VWF and phospholipids and destroys a major FVIII antigenic determinant involved in inhibitor development.

d'Oiron R, Lavergne JM, Lavend'homme R, Benhida A, Bordet JC, Negrier C, Peerlinck K, Vermylen J, Saint-Remy JM, Jacquemin M. d'Oiron R, et al. Blood. 2004 Jan 1;103(1):155-7. doi: 10.1182/blood-2003-04-1321. Epub 2003 Sep 11. Blood. 2004. PMID: 12969981 Free article.

6

Impact of choice of treatment for bleeding episodes on inhibitor outcome in patients with mild/moderate hemophilia a and inhibitors.

d'Oiron R, Volot F, Reynaud J, Peerlinck K, Goudemand J, Guérois C, Rothschild C, Chambost H, Borel-Derlon A, Roussel-Robert V, Marquès-Verdier A, Lienhart A, Berthier AM, Moreau P, Lambert T; MHAI Study Group. d'Oiron R, et al. Semin Hematol. 2006 Jan;43(1 Suppl 1):S3-9. doi: 10.1053/j.seminhematol.2005.11.002. Semin Hematol. 2006. PMID: 16427382

7

Detection of 95 novel mutations in coagulation factor VIII gene F8 responsible for hemophilia A: results from a single institution.

Guillet B, Lambert T, d'Oiron R, Proulle V, Plantier JL, Rafowicz A, Peynet J, Costa JM, Bendelac L, Laurian Y, Lavergne JM. Guillet B, et al. Hum Mutat. 2006 Jul;27(7):676-85. doi: 10.1002/humu.20345. Hum Mutat. 2006. PMID: 16786531

8

Factor VIII bypasses CD91/LRP for endocytosis by dendritic cells leading to T-cell activation.

Dasgupta S, Navarrete AM, André S, Wootla B, Delignat S, Repessé Y, Bayry J, Nicoletti A, Saenko EL, d'Oiron R, Jacquemin M, Saint-Remy JM, Kaveri SV, Lacroix-Desmazes S. Dasgupta S, et al. Haematologica. 2008 Jan;93(1):83-9. doi: 10.3324/haematol.11535. Haematologica. 2008. PMID: 18166789 Free article.

9

Factor VIII genotype and inhibitor development in patients with haemophilia A: highest risk in patients with splice site mutations.

Boekhorst J, Lari GR, D'Oiron R, Costa JM, Nováková IR, Ala FA, Lavergne JM, VAN Heerde WL. Boekhorst J, et al. Haemophilia. 2008 Jul;14(4):729-35. doi: 10.1111/j.1365-2516.2008.01694.x. Epub 2008 May 12. Haemophilia. 2008. PMID: 18503540

10

Successful immune tolerance induction by FVIII in hemophilia A patients with inhibitor may occur without deletion of FVIII-specific T cells.

Pautard B, D'Oiron R, Li Thiao Te V, Lavend'homme R, Saint-Remy JM, Peerlinck K, Jacquemin M. Pautard B, et al. J Thromb Haemost. 2011 Jun;9(6):1163-70. doi: 10.1111/j.1538-7836.2011.04267.x. J Thromb Haemost. 2011. PMID: 21645224 Free article. Clinical Trial.

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