Witek RP - Search Results

1

Fate-mapping evidence that hepatic stellate cells are epithelial progenitors in adult mouse livers.

Yang L, Jung Y, Omenetti A, Witek RP, Choi S, Vandongen HM, Huang J, Alpini GD, Diehl AM. Yang L, et al. Among authors: witek rp. Stem Cells. 2008 Aug;26(8):2104-13. doi: 10.1634/stemcells.2008-0115. Epub 2008 May 29. Stem Cells. 2008. PMID: 18511600 Free PMC article.

2

Accumulation of hedgehog-responsive progenitors parallels alcoholic liver disease severity in mice and humans.

Jung Y, Brown KD, Witek RP, Omenetti A, Yang L, Vandongen M, Milton RJ, Hines IN, Rippe RA, Spahr L, Rubbia-Brandt L, Diehl AM. Jung Y, et al. Among authors: witek rp. Gastroenterology. 2008 May;134(5):1532-43. doi: 10.1053/j.gastro.2008.02.022. Epub 2008 Feb 14. Gastroenterology. 2008. PMID: 18471524 Free PMC article.

3

Hedgehog signaling regulates epithelial-mesenchymal transition during biliary fibrosis in rodents and humans.

Omenetti A, Porrello A, Jung Y, Yang L, Popov Y, Choi SS, Witek RP, Alpini G, Venter J, Vandongen HM, Syn WK, Baroni GS, Benedetti A, Schuppan D, Diehl AM. Omenetti A, et al. Among authors: witek rp. J Clin Invest. 2008 Oct;118(10):3331-42. doi: 10.1172/JCI35875. J Clin Invest. 2008. PMID: 18802480 Free PMC article.

4

Liver cell-derived microparticles activate hedgehog signaling and alter gene expression in hepatic endothelial cells.

Witek RP, Yang L, Liu R, Jung Y, Omenetti A, Syn WK, Choi SS, Cheong Y, Fearing CM, Agboola KM, Chen W, Diehl AM. Witek RP, et al. Gastroenterology. 2009 Jan;136(1):320-330.e2. doi: 10.1053/j.gastro.2008.09.066. Epub 2008 Oct 7. Gastroenterology. 2009. PMID: 19013163 Free PMC article.

5

Hedgehog pathway activation and epithelial-to-mesenchymal transitions during myofibroblastic transformation of rat hepatic cells in culture and cirrhosis.

Choi SS, Omenetti A, Witek RP, Moylan CA, Syn WK, Jung Y, Yang L, Sudan DL, Sicklick JK, Michelotti GA, Rojkind M, Diehl AM. Choi SS, et al. Among authors: witek rp. Am J Physiol Gastrointest Liver Physiol. 2009 Dec;297(6):G1093-106. doi: 10.1152/ajpgi.00292.2009. Epub 2009 Oct 8. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19815628 Free PMC article.

6

Signals from dying hepatocytes trigger growth of liver progenitors.

Jung Y, Witek RP, Syn WK, Choi SS, Omenetti A, Premont R, Guy CD, Diehl AM. Jung Y, et al. Among authors: witek rp. Gut. 2010 May;59(5):655-65. doi: 10.1136/gut.2009.204354. Gut. 2010. PMID: 20427400 Free PMC article.

7

Activation of Rac1 promotes hedgehog-mediated acquisition of the myofibroblastic phenotype in rat and human hepatic stellate cells.

Choi SS, Witek RP, Yang L, Omenetti A, Syn WK, Moylan CA, Jung Y, Karaca GF, Teaberry VS, Pereira TA, Wang J, Ren XR, Diehl AM. Choi SS, et al. Among authors: witek rp. Hepatology. 2010 Jul;52(1):278-90. doi: 10.1002/hep.23649. Hepatology. 2010. PMID: 20578145 Free PMC article.

8

Leptin promotes the myofibroblastic phenotype in hepatic stellate cells by activating the hedgehog pathway.

Choi SS, Syn WK, Karaca GF, Omenetti A, Moylan CA, Witek RP, Agboola KM, Jung Y, Michelotti GA, Diehl AM. Choi SS, et al. Among authors: witek rp. J Biol Chem. 2010 Nov 19;285(47):36551-60. doi: 10.1074/jbc.M110.168542. Epub 2010 Sep 14. J Biol Chem. 2010. PMID: 20843817 Free PMC article.

9

The hedgehog pathway regulates remodelling responses to biliary obstruction in rats.

Omenetti A, Popov Y, Jung Y, Choi SS, Witek RP, Yang L, Brown KD, Schuppan D, Diehl AM. Omenetti A, et al. Among authors: witek rp. Gut. 2008 Sep;57(9):1275-82. doi: 10.1136/gut.2008.148619. Epub 2008 Mar 28. Gut. 2008. PMID: 18375471

10

Genetic differences in oxidative stress and inflammatory responses to diet-induced obesity do not alter liver fibrosis in mice.

Syn WK, Yang L, Chiang DJ, Qian Y, Jung Y, Karaca G, Choi SS, Witek RP, Omenetti A, Pereira TA, Diehl AM. Syn WK, et al. Among authors: witek rp. Liver Int. 2009 Sep;29(8):1262-72. doi: 10.1111/j.1478-3231.2009.02036.x. Epub 2009 Apr 20. Liver Int. 2009. PMID: 19490416 Free PMC article.

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