Botta M - Search Results

1

1-[(3-Aryloxy-3-aryl)propyl]-1H-imidazoles, new imidazoles with potent activity against Candida albicans and dermatophytes. Synthesis, structure-activity relationship, and molecular modeling studies.

La Regina G, D'Auria FD, Tafi A, Piscitelli F, Olla S, Caporuscio F, Nencioni L, Cirilli R, La Torre F, De Melo NR, Kelly SL, Lamb DC, Artico M, Botta M, Palamara AT, Silvestri R. La Regina G, et al. Among authors: botta m. J Med Chem. 2008 Jul 10;51(13):3841-55. doi: 10.1021/jm800009r. Epub 2008 Jun 5. J Med Chem. 2008. PMID: 18529046

2

Antifungal agents. 10. New derivatives of 1-[(aryl)[4-aryl-1H-pyrrol-3-yl]methyl]-1H-imidazole, synthesis, anti-candida activity, and quantitative structure-analysis relationship studies.

Tafi A, Costi R, Botta M, Di Santo R, Corelli F, Massa S, Ciacci A, Manetti F, Artico M. Tafi A, et al. Among authors: botta m. J Med Chem. 2002 Jun 20;45(13):2720-32. doi: 10.1021/jm011087h. J Med Chem. 2002. PMID: 12061875

3

Synthesis, cannabinoid receptor affinity, and molecular modeling studies of substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides.

Silvestri R, Cascio MG, La Regina G, Piscitelli F, Lavecchia A, Brizzi A, Pasquini S, Botta M, Novellino E, Di Marzo V, Corelli F. Silvestri R, et al. Among authors: botta m. J Med Chem. 2008 Mar 27;51(6):1560-76. doi: 10.1021/jm070566z. Epub 2008 Feb 23. J Med Chem. 2008. PMID: 18293908

4

Synthesis, biological evaluation and structure-activity correlation study of a series of imidazol-based compounds as Candida albicans inhibitors.

Moraca F, De Vita D, Pandolfi F, Di Santo R, Costi R, Cirilli R, D'Auria FD, Panella S, Palamara AT, Simonetti G, Botta M, Scipione L. Moraca F, et al. Among authors: botta m. Eur J Med Chem. 2014 Aug 18;83:665-73. doi: 10.1016/j.ejmech.2014.07.001. Epub 2014 Jul 1. Eur J Med Chem. 2014. PMID: 25010937

5

Indolylarylsulfones carrying a heterocyclic tail as very potent and broad spectrum HIV-1 non-nucleoside reverse transcriptase inhibitors.

Famiglini V, La Regina G, Coluccia A, Pelliccia S, Brancale A, Maga G, Crespan E, Badia R, Riveira-Muñoz E, Esté JA, Ferretti R, Cirilli R, Zamperini C, Botta M, Schols D, Limongelli V, Agostino B, Novellino E, Silvestri R. Famiglini V, et al. Among authors: botta m. J Med Chem. 2014 Dec 11;57(23):9945-57. doi: 10.1021/jm5011622. Epub 2014 Nov 24. J Med Chem. 2014. PMID: 25418038

6

New 1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides inhibit hepatitis C virus replication via suppression of cyclooxygenase-2.

Manvar D, Pelliccia S, La Regina G, Famiglini V, Coluccia A, Ruggieri A, Anticoli S, Lee JC, Basu A, Cevik O, Nencioni L, Palamara AT, Zamperini C, Botta M, Neyts J, Leyssen P, Kaushik-Basu N, Silvestri R. Manvar D, et al. Among authors: botta m. Eur J Med Chem. 2015 Jan 27;90:497-506. doi: 10.1016/j.ejmech.2014.11.042. Epub 2014 Nov 27. Eur J Med Chem. 2015. PMID: 25483263 Free article.

7

Alpha(1)-adrenoceptor antagonists. 4. Pharmacophore-based design, synthesis, and biological evaluation of new imidazo-, benzimidazo-, and indoloarylpiperazine derivatives.

Betti L, Botta M, Corelli F, Floridi M, Giannaccini G, Maccari L, Manetti F, Strappaghetti G, Tafi A, Corsano S. Betti L, et al. Among authors: botta m. J Med Chem. 2002 Aug 15;45(17):3603-11. doi: 10.1021/jm011077g. J Med Chem. 2002. PMID: 12166933

8

Synthesis, molecular modeling studies, and pharmacological activity of selective A(1) receptor antagonists.

Bondavalli F, Botta M, Bruno O, Ciacci A, Corelli F, Fossa P, Lucacchini A, Manetti F, Martini C, Menozzi G, Mosti L, Ranise A, Schenone S, Tafi A, Trincavellic ML. Bondavalli F, et al. Among authors: botta m. J Med Chem. 2002 Oct 24;45(22):4875-87. doi: 10.1021/jm0209580. J Med Chem. 2002. PMID: 12383013

9

AMBER force field implementation of the boronate function to simulate the inhibition of beta-lactamases by alkyl and aryl boronic acids.

Tafi A, Agamennone M, Tortorella P, Alcaro S, Gallina C, Botta M. Tafi A, et al. Among authors: botta m. Eur J Med Chem. 2005 Nov;40(11):1134-42. doi: 10.1016/j.ejmech.2005.06.011. Epub 2005 Sep 8. Eur J Med Chem. 2005. PMID: 16153747

10

Pharmacophore based receptor modeling: the case of adenosine A3 receptor antagonists. An approach to the optimization of protein models.

Tafi A, Bernardini C, Botta M, Corelli F, Andreini M, Martinelli A, Ortore G, Baraldi PG, Fruttarolo F, Borea PA, Tuccinardi T. Tafi A, et al. Among authors: botta m. J Med Chem. 2006 Jul 13;49(14):4085-97. doi: 10.1021/jm051112+. J Med Chem. 2006. PMID: 16821770

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