Sekine M - Search Results

1

O-selective condensation using P-N bond cleavage in RNA synthesis without base protection.

Ohkubo A, Kuwayama Y, Kudo T, Tsunoda H, Seio K, Sekine M. Ohkubo A, et al. Among authors: sekine m. Org Lett. 2008 Jul 3;10(13):2793-6. doi: 10.1021/ol800911b. Epub 2008 Jun 6. Org Lett. 2008. PMID: 18533674

2

Proton-block strategy for the synthesis of oligodeoxynucleotides without base protection, capping reaction, and P-N bond cleavage reaction.

Sekine M, Ohkubo A, Seio K. Sekine M, et al. J Org Chem. 2003 Jul 11;68(14):5478-92. doi: 10.1021/jo034204k. J Org Chem. 2003. PMID: 12839438

3

A new strategy for the synthesis of oligodeoxynucleotides in the phosphoramidite method without base protection via phosphite intermediates.

Ohkubo A, Ezawa Y, Seio K, Sekine M. Ohkubo A, et al. Among authors: sekine m. Nucleic Acids Res Suppl. 2002;(2):29-30. doi: 10.1093/nass/2.1.29. Nucleic Acids Res Suppl. 2002. PMID: 12903089

4

Convenient synthesis of N-unprotected deoxynucleoside 3'-phosphoramidite building blocks by selective deacylation of N-acylated species and their facile conversion to other N-functionalized derivatives.

Ohkubo A, Sakamoto K, Miyata K, Taguchi H, Seio K, Sekine M. Ohkubo A, et al. Among authors: sekine m. Org Lett. 2005 Nov 24;7(24):5389-92. doi: 10.1021/ol051949z. Org Lett. 2005. PMID: 16288513

5

A general method for the synthesis of 2'-O-cyanoethylated oligoribonucleotides having promising hybridization affinity for DNA and RNA and enhanced nuclease resistance.

Saneyoshi H, Seio K, Sekine M. Saneyoshi H, et al. Among authors: sekine m. J Org Chem. 2005 Dec 9;70(25):10453-60. doi: 10.1021/jo051741r. J Org Chem. 2005. PMID: 16323857

6

Synthesis and properties of a new fluorescent bicyclic 4-N-carbamoyldeoxycytidine derivative.

Miyata K, Tamamushi R, Ohkubo A, Taguchi H, Seio K, Santa T, Sekine M. Miyata K, et al. Among authors: sekine m. Org Lett. 2006 Apr 13;8(8):1545-8. doi: 10.1021/ol053125n. Org Lett. 2006. PMID: 16597106

7

Synthesis and fluorescent properties of bi- and tricyclic 4-N-carbamoyldeoxycytidine derivatives.

Miyata K, Mineo R, Tamamushi R, Mizuta M, Ohkubo A, Taguchi H, Seio K, Santa T, Sekine M. Miyata K, et al. Among authors: sekine m. J Org Chem. 2007 Jan 5;72(1):102-8. doi: 10.1021/jo0617767. J Org Chem. 2007. PMID: 17194087

8

An effective method for the in situ synthesis of DNA-CPG conjugates using chemical ligation technology as tools for SNP analysis.

Ohkubo A, Tanaka K, Taguchi H, Seio K, Nagasawa H, Tsukahara T, Sekine M. Ohkubo A, et al. Among authors: sekine m. Bioorg Med Chem Lett. 2007 Nov 1;17(21):5969-73. doi: 10.1016/j.bmcl.2007.07.066. Epub 2007 Aug 21. Bioorg Med Chem Lett. 2007. PMID: 17845851

9

Synthesis of branched oligonucleotides with three different sequences using an oxidatively removable tritylthio group.

Utagawa E, Ohkubo A, Sekine M, Seio K. Utagawa E, et al. Among authors: sekine m. J Org Chem. 2007 Oct 26;72(22):8259-66. doi: 10.1021/jo071173a. Epub 2007 Sep 27. J Org Chem. 2007. PMID: 17900140

10

Synthesis and properties of oligonucleotides with iodo-substituted aromatic aglycons: investigation of possible halogen bonding base pairs.

Tawarada R, Seio K, Sekine M. Tawarada R, et al. Among authors: sekine m. J Org Chem. 2008 Jan 18;73(2):383-90. doi: 10.1021/jo701634t. Epub 2007 Dec 15. J Org Chem. 2008. PMID: 18081343

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