Shalev A - Search Results

1

Thioredoxin-interacting protein deficiency induces Akt/Bcl-xL signaling and pancreatic beta-cell mass and protects against diabetes.

Chen J, Hui ST, Couto FM, Mungrue IN, Davis DB, Attie AD, Lusis AJ, Davis RA, Shalev A. Chen J, et al. Among authors: shalev a. FASEB J. 2008 Oct;22(10):3581-94. doi: 10.1096/fj.08-111690. Epub 2008 Jun 13. FASEB J. 2008. PMID: 18552236 Free PMC article.

2

Exenatide inhibits beta-cell apoptosis by decreasing thioredoxin-interacting protein.

Chen J, Couto FM, Minn AH, Shalev A. Chen J, et al. Among authors: shalev a. Biochem Biophys Res Commun. 2006 Aug 4;346(3):1067-74. doi: 10.1016/j.bbrc.2006.06.027. Epub 2006 Jun 13. Biochem Biophys Res Commun. 2006. PMID: 16782054

3

Metabolism-independent sugar effects on gene transcription: the role of 3-O-methylglucose.

Minn AH, Couto FM, Shalev A. Minn AH, et al. Among authors: shalev a. Biochemistry. 2006 Sep 19;45(37):11047-51. doi: 10.1021/bi0603625. Biochemistry. 2006. PMID: 16964965

4

Thioredoxin-interacting protein: a critical link between glucose toxicity and beta-cell apoptosis.

Chen J, Saxena G, Mungrue IN, Lusis AJ, Shalev A. Chen J, et al. Among authors: shalev a. Diabetes. 2008 Apr;57(4):938-44. doi: 10.2337/db07-0715. Epub 2008 Jan 2. Diabetes. 2008. PMID: 18171713 Free PMC article.

5

Diabetes induces and calcium channel blockers prevent cardiac expression of proapoptotic thioredoxin-interacting protein.

Chen J, Cha-Molstad H, Szabo A, Shalev A. Chen J, et al. Among authors: shalev a. Am J Physiol Endocrinol Metab. 2009 May;296(5):E1133-9. doi: 10.1152/ajpendo.90944.2008. Epub 2009 Mar 3. Am J Physiol Endocrinol Metab. 2009. PMID: 19258488 Free PMC article.

6

Intracellular shuttling and mitochondrial function of thioredoxin-interacting protein.

Saxena G, Chen J, Shalev A. Saxena G, et al. Among authors: shalev a. J Biol Chem. 2010 Feb 5;285(6):3997-4005. doi: 10.1074/jbc.M109.034421. Epub 2009 Dec 3. J Biol Chem. 2010. PMID: 19959470 Free PMC article.

7

Increased insulin translation from an insulin splice-variant overexpressed in diabetes, obesity, and insulin resistance.

Minn AH, Lan H, Rabaglia ME, Harlan DM, Peculis BA, Attie AD, Shalev A. Minn AH, et al. Among authors: shalev a. Mol Endocrinol. 2005 Mar;19(3):794-803. doi: 10.1210/me.2004-0119. Epub 2004 Nov 18. Mol Endocrinol. 2005. PMID: 15550470

8

Exenatide blocks JAK1-STAT1 in pancreatic beta cells.

Couto FM, Minn AH, Pise-Masison CA, Radonovich M, Brady JN, Hanson M, Fernandez LA, Wang P, Kendziorski C, Shalev A. Couto FM, et al. Among authors: shalev a. Metabolism. 2007 Jul;56(7):915-8. doi: 10.1016/j.metabol.2007.02.004. Metabolism. 2007. PMID: 17570252

9

Glucose-stimulated expression of Txnip is mediated by carbohydrate response element-binding protein, p300, and histone H4 acetylation in pancreatic beta cells.

Cha-Molstad H, Saxena G, Chen J, Shalev A. Cha-Molstad H, et al. Among authors: shalev a. J Biol Chem. 2009 Jun 19;284(25):16898-16905. doi: 10.1074/jbc.M109.010504. Epub 2009 May 1. J Biol Chem. 2009. PMID: 19411249 Free PMC article.

10

Lack of TXNIP protects against mitochondria-mediated apoptosis but not against fatty acid-induced ER stress-mediated beta-cell death.

Chen J, Fontes G, Saxena G, Poitout V, Shalev A. Chen J, et al. Among authors: shalev a. Diabetes. 2010 Feb;59(2):440-7. doi: 10.2337/db09-0949. Epub 2009 Oct 29. Diabetes. 2010. PMID: 19875615 Free PMC article.

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