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Combinatorial antileukemic disruption of oxidative homeostasis and mitochondrial stability by the redox reactive thalidomide 2-(2,4-difluoro-phenyl)-4,5,6,7-tetrafluoro-1H-isoindole-1,3(2H)-dione (CPS49) and flavopiridol.
Ge Y, Byun JS, De Luca P, Gueron G, Yabe IM, Sadiq-Ali SG, Figg WD, Quintero J, Haggerty CM, Li QQ, De Siervi A, Gardner K. Ge Y, et al. Mol Pharmacol. 2008 Sep;74(3):872-83. doi: 10.1124/mol.107.040808. Epub 2008 Jun 12. Mol Pharmacol. 2008. PMID: 18556456 Free PMC article.
Selective leukemic-cell killing by a novel functional class of thalidomide analogs.
Ge Y, Montano I, Rustici G, Freebern WJ, Haggerty CM, Cui W, Ponciano-Jackson D, Chandramouli GV, Gardner ER, Figg WD, Abu-Asab M, Tsokos M, Jackson SH, Gardner K. Ge Y, et al. Blood. 2006 Dec 15;108(13):4126-35. doi: 10.1182/blood-2006-04-017046. Epub 2006 Aug 29. Blood. 2006. PMID: 16940421 Free PMC article.
Antiproliferative mechanisms of action of the flavin dehydrogenase inhibitors diphenylene iodonium and di-2-thienyliodonium based on molecular profiling of the NCI-60 human tumor cell panel.
Doroshow JH, Juhasz A, Ge Y, Holbeck S, Lu J, Antony S, Wu Y, Jiang G, Roy K. Doroshow JH, et al. Among authors: ge y. Biochem Pharmacol. 2012 May 1;83(9):1195-207. doi: 10.1016/j.bcp.2012.01.022. Epub 2012 Jan 24. Biochem Pharmacol. 2012. PMID: 22305747 Free PMC article.
7,106 results