Siddiqui MA - Search Results

1

Comprehensive structural studies of 2',3'-difluorinated nucleosides: comparison of theory, solution, and solid state.

Barchi JJ Jr, Karki RG, Nicklaus MC, Siddiqui MA, George C, Mikhailopulo IA, Marquez VE. Barchi JJ Jr, et al. Among authors: siddiqui ma. J Am Chem Soc. 2008 Jul 16;130(28):9048-57. doi: 10.1021/ja800964g. Epub 2008 Jun 18. J Am Chem Soc. 2008. PMID: 18558684 Free PMC article.

2

Adenosine deaminase prefers a distinct sugar ring conformation for binding and catalysis: kinetic and structural studies.

Ford H Jr, Dai F, Mu L, Siddiqui MA, Nicklaus MC, Anderson L, Marquez VE, Barchi JJ Jr. Ford H Jr, et al. Among authors: siddiqui ma. Biochemistry. 2000 Mar 14;39(10):2581-92. doi: 10.1021/bi992112c. Biochemistry. 2000. PMID: 10704207

3

A 4'-C-ethynyl-2',3'-dideoxynucleoside analogue highlights the role of the 3'-OH in anti-HIV active 4'-C-ethynyl-2'-deoxy nucleosides.

Siddiqui MA, Hughes SH, Boyer PL, Mitsuya H, Van QN, George C, Sarafinanos SG, Marquez VE. Siddiqui MA, et al. J Med Chem. 2004 Oct 7;47(21):5041-8. doi: 10.1021/jm049550o. J Med Chem. 2004. PMID: 15456247

4

The triphosphate of beta-D-4'-C-ethynyl-2',3'-dideoxycytidine is the preferred enantiomer substrate for HIV reverse transcriptase.

Siddiqui MA, Marquez VE. Siddiqui MA, et al. Bioorg Med Chem. 2007 Jan 1;15(1):283-7. doi: 10.1016/j.bmc.2006.09.061. Epub 2006 Sep 29. Bioorg Med Chem. 2007. PMID: 17046266 Free PMC article.

5

What are the consequences of freezing the anomeric effect in nucleosides?

Marquez VE, Sun G, Siddiqui MA, Lee YC, Barchi JJ Jr, Filippov IV, Landsman NA, Kelley JA. Marquez VE, et al. Among authors: siddiqui ma. Nucleic Acids Symp Ser (Oxf). 2008;(52):543-4. doi: 10.1093/nass/nrn275. Nucleic Acids Symp Ser (Oxf). 2008. PMID: 18776494 Free PMC article.

6

Using conformationally locked nucleosides to calibrate the anomeric effect: Implications for glycosyl bond stability.

Moon HR, Siddiqui MA, Sun G, Filippov IV, Landsman NA, Lee YC, Adams KM, Barchi JJ, Deschamps JR, Nicklaus MC, Kelley JA, Marquez VE. Moon HR, et al. Among authors: siddiqui ma. Tetrahedron. 2010 Aug 21;66(34):6707-6717. doi: 10.1016/j.tet.2010.06.044. Tetrahedron. 2010. PMID: 21052524 Free PMC article.

7

Conformational analysis of the complete series of 2' and 3' monofluorinated dideoxyuridines.

Barchi JJ Jr, Jeong LS, Siddiqui MA, Marquez VE. Barchi JJ Jr, et al. Among authors: siddiqui ma. J Biochem Biophys Methods. 1997 Feb 1;34(1):11-29. doi: 10.1016/s0165-022x(96)00032-2. J Biochem Biophys Methods. 1997. PMID: 9089381

8

Conformationally restricted nucleosides. The reaction of adenosine deaminase with substrates built on a bicyclo[3.1.0]hexane template.

Marquez VE, Russ P, Alonso R, Siddiqui MA, Shin KJ, George C, Nicklaus MC, Dai F, Ford H Jr. Marquez VE, et al. Among authors: siddiqui ma. Nucleosides Nucleotides. 1999 Apr-May;18(4-5):521-30. doi: 10.1080/15257779908041487. Nucleosides Nucleotides. 1999. PMID: 10432643

9

The "beta-fluorine effect" in the non-metal hydride radical deoxygenation of fluorine-containing nucleoside xanthates.

Siddiqui MA, Driscoll JS, Abushanab E, Kelley JA, Barchi JJ Jr, Marquez VE. Siddiqui MA, et al. Nucleosides Nucleotides Nucleic Acids. 2000 Jan-Feb;19(1-2):1-12. doi: 10.1080/15257770008032993. Nucleosides Nucleotides Nucleic Acids. 2000. PMID: 10772699

10

Interactions of conformationally biased north and south 2'-fluoro-2', 3'-dideoxynucleoside 5'-triphosphates with the active site of HIV-1 reverse transcriptase.

Mu L, Sarafianos SG, Nicklaus MC, Russ P, Siddiqui MA, Ford H Jr, Mitsuya H, Le R, Kodama E, Meier C, Knispel T, Anderson L, Barchi JJ Jr, Marquez VE. Mu L, et al. Among authors: siddiqui ma. Biochemistry. 2000 Sep 19;39(37):11205-15. doi: 10.1021/bi001090n. Biochemistry. 2000. PMID: 10985766

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