Lebel M - Search Results

1

The strand separation and nuclease activities associated with YB-1 are dispensable for cisplatin resistance but overexpression of YB-1 in MCF7 and MDA-MB-231 breast tumor cells generates several chemoresistance signatures.

Guay D, Evoy AA, Paquet E, Garand C, Bachvarova M, Bachvarov D, Lebel M. Guay D, et al. Among authors: lebel m. Int J Biochem Cell Biol. 2008;40(11):2492-507. doi: 10.1016/j.biocel.2008.04.011. Epub 2008 May 15. Int J Biochem Cell Biol. 2008. PMID: 18571458

2

YB-1 promotes strand separation in vitro of duplex DNA containing either mispaired bases or cisplatin modifications, exhibits endonucleolytic activities and binds several DNA repair proteins.

Gaudreault I, Guay D, Lebel M. Gaudreault I, et al. Among authors: lebel m. Nucleic Acids Res. 2004 Jan 12;32(1):316-27. doi: 10.1093/nar/gkh170. Print 2004. Nucleic Acids Res. 2004. PMID: 14718551 Free PMC article.

3

In vivo misregulation of genes involved in apoptosis, development and oxidative stress in mice lacking both functional Werner syndrome protein and poly(ADP-ribose) polymerase-1.

Deschênes F, Massip L, Garand C, Lebel M. Deschênes F, et al. Among authors: lebel m. Hum Mol Genet. 2005 Nov 1;14(21):3293-308. doi: 10.1093/hmg/ddi362. Epub 2005 Sep 29. Hum Mol Genet. 2005. PMID: 16195394

4

Increased insulin, triglycerides, reactive oxygen species, and cardiac fibrosis in mice with a mutation in the helicase domain of the Werner syndrome gene homologue.

Massip L, Garand C, Turaga RV, Deschênes F, Thorin E, Lebel M. Massip L, et al. Among authors: lebel m. Exp Gerontol. 2006 Feb;41(2):157-68. doi: 10.1016/j.exger.2005.10.011. Epub 2005 Dec 5. Exp Gerontol. 2006. PMID: 16330174

5

Formation of a nuclear complex containing the p53 tumor suppressor, YB-1, and the Werner syndrome gene product in cells treated with UV light.

Guay D, Gaudreault I, Massip L, Lebel M. Guay D, et al. Among authors: lebel m. Int J Biochem Cell Biol. 2006;38(8):1300-13. doi: 10.1016/j.biocel.2006.01.008. Epub 2006 Feb 24. Int J Biochem Cell Biol. 2006. PMID: 16584908

6

The human endonuclease III enzyme is a relevant target to potentiate cisplatin cytotoxicity in Y-box-binding protein-1 overexpressing tumor cells.

Guay D, Garand C, Reddy S, Schmutte C, Lebel M. Guay D, et al. Among authors: lebel m. Cancer Sci. 2008 Apr;99(4):762-9. doi: 10.1111/j.1349-7006.2008.00739.x. Epub 2008 Feb 27. Cancer Sci. 2008. PMID: 18307537 Free PMC article.

7

Novel DNA mismatch-repair activity involving YB-1 in human mitochondria.

de Souza-Pinto NC, Mason PA, Hashiguchi K, Weissman L, Tian J, Guay D, Lebel M, Stevnsner TV, Rasmussen LJ, Bohr VA. de Souza-Pinto NC, et al. Among authors: lebel m. DNA Repair (Amst). 2009 Jun 4;8(6):704-19. doi: 10.1016/j.dnarep.2009.01.021. Epub 2009 Mar 9. DNA Repair (Amst). 2009. PMID: 19272840 Free PMC article.

8

The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responses.

Turaga RV, Paquet ER, Sild M, Vignard J, Garand C, Johnson FB, Masson JY, Lebel M. Turaga RV, et al. Among authors: lebel m. Cell Cycle. 2009 Jul 1;8(13):2080-92. doi: 10.4161/cc.8.13.8925. Epub 2009 Jul 5. Cell Cycle. 2009. PMID: 19502800

9

Vitamin C restores healthy aging in a mouse model for Werner syndrome.

Massip L, Garand C, Paquet ER, Cogger VC, O'Reilly JN, Tworek L, Hatherell A, Taylor CG, Thorin E, Zahradka P, Le Couteur DG, Lebel M. Massip L, et al. Among authors: lebel m. FASEB J. 2010 Jan;24(1):158-72. doi: 10.1096/fj.09-137133. Epub 2009 Sep 9. FASEB J. 2010. PMID: 19741171 Free PMC article.

10

Depletion of WRN protein causes RACK1 to activate several protein kinase C isoforms.

Massip L, Garand C, Labbé A, Perreault E, Turaga RV, Bohr VA, Lebel M. Massip L, et al. Among authors: lebel m. Oncogene. 2010 Mar 11;29(10):1486-97. doi: 10.1038/onc.2009.443. Epub 2009 Dec 7. Oncogene. 2010. PMID: 19966859 Free PMC article.

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