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The closed conformation of the LDL receptor is destabilized by the low Ca(++) concentration but favored by the high Mg(++) concentration in the endosome.
Martínez-Oliván J, Arias-Moreno X, Hurtado-Guerrero R, Carrodeguas JA, Miguel-Romero L, Marina A, Bruscolini P, Sancho J. Martínez-Oliván J, et al. Among authors: arias moreno x. FEBS Lett. 2015 Nov 30;589(23):3534-40. doi: 10.1016/j.febslet.2015.10.014. Epub 2015 Oct 23. FEBS Lett. 2015. PMID: 26526611 Free article.
The closed conformation of the LDL receptor is destabilized by the low Ca(++) concentration but favored by the high Mg(++) concentration in the endosome.
Martínez-Oliván J, Arias-Moreno X, Hurtado-Guerrero R, Carrodeguas JA, Miguel-Romero L, Marina A, Bruscolini P, Sancho J. Martínez-Oliván J, et al. Among authors: arias moreno x. FEBS Lett. 2016 Jul;590(14):2322. doi: 10.1002/1873-3468.12270. FEBS Lett. 2016. PMID: 27461443 Free article. No abstract available.
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