Rosen H - Search Results

1

Local not systemic modulation of dendritic cell S1P receptors in lung blunts virus-specific immune responses to influenza.

Marsolais D, Hahm B, Edelmann KH, Walsh KB, Guerrero M, Hatta Y, Kawaoka Y, Roberts E, Oldstone MB, Rosen H. Marsolais D, et al. Among authors: rosen h. Mol Pharmacol. 2008 Sep;74(3):896-903. doi: 10.1124/mol.108.048769. Epub 2008 Jun 24. Mol Pharmacol. 2008. PMID: 18577684 Free PMC article.

2

Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate.

Sanna MG, Liao J, Jo E, Alfonso C, Ahn MY, Peterson MS, Webb B, Lefebvre S, Chun J, Gray N, Rosen H. Sanna MG, et al. Among authors: rosen h. J Biol Chem. 2004 Apr 2;279(14):13839-48. doi: 10.1074/jbc.M311743200. Epub 2004 Jan 19. J Biol Chem. 2004. PMID: 14732717 Free article.

3

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network.

Rosen H, Goetzl EJ. Rosen H, et al. Nat Rev Immunol. 2005 Jul;5(7):560-70. doi: 10.1038/nri1650. Nat Rev Immunol. 2005. PMID: 15999095 Review.

4

CD69 down-modulation and inhibition of thymic egress by short- and long-term selective chemical agonism of sphingosine 1-phosphate receptors.

Alfonso C, McHeyzer-Williams MG, Rosen H. Alfonso C, et al. Among authors: rosen h. Eur J Immunol. 2006 Jan;36(1):149-59. doi: 10.1002/eji.200535127. Eur J Immunol. 2006. PMID: 16342326 Free article.

5

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

Sanna MG, Wang SK, Gonzalez-Cabrera PJ, Don A, Marsolais D, Matheu MP, Wei SH, Parker I, Jo E, Cheng WC, Cahalan MD, Wong CH, Rosen H. Sanna MG, et al. Among authors: rosen h. Nat Chem Biol. 2006 Aug;2(8):434-41. doi: 10.1038/nchembio804. Epub 2006 Jul 9. Nat Chem Biol. 2006. PMID: 16829954

6

Tipping the gatekeeper: S1P regulation of endothelial barrier function.

Rosen H, Sanna MG, Cahalan SM, Gonzalez-Cabrera PJ. Rosen H, et al. Trends Immunol. 2007 Mar;28(3):102-7. doi: 10.1016/j.it.2007.01.007. Epub 2007 Feb 5. Trends Immunol. 2007. PMID: 17276731 Review.

7

Essential requirement for sphingosine kinase 2 in a sphingolipid apoptosis pathway activated by FTY720 analogues.

Don AS, Martinez-Lamenca C, Webb WR, Proia RL, Roberts E, Rosen H. Don AS, et al. Among authors: rosen h. J Biol Chem. 2007 May 25;282(21):15833-42. doi: 10.1074/jbc.M609124200. Epub 2007 Mar 30. J Biol Chem. 2007. PMID: 17400555 Free article.

8

Application of beta-lactamase enzyme complementation to the high-throughput screening of toll-like receptor signaling inhibitors.

Lee HK, Brown SJ, Rosen H, Tobias PS. Lee HK, et al. Among authors: rosen h. Mol Pharmacol. 2007 Oct;72(4):868-75. doi: 10.1124/mol.107.038349. Epub 2007 Jul 5. Mol Pharmacol. 2007. PMID: 17615244

9

Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation.

Niessen F, Schaffner F, Furlan-Freguia C, Pawlinski R, Bhattacharjee G, Chun J, Derian CK, Andrade-Gordon P, Rosen H, Ruf W. Niessen F, et al. Among authors: rosen h. Nature. 2008 Apr 3;452(7187):654-8. doi: 10.1038/nature06663. Epub 2008 Feb 27. Nature. 2008. PMID: 18305483

10

Ligand-binding pocket shape differences between sphingosine 1-phosphate (S1P) receptors S1P1 and S1P3 determine efficiency of chemical probe identification by ultrahigh-throughput screening.

Schürer SC, Brown SJ, Gonzalez-Cabrera PJ, Schaeffer MT, Chapman J, Jo E, Chase P, Spicer T, Hodder P, Rosen H. Schürer SC, et al. Among authors: rosen h. ACS Chem Biol. 2008 Aug 15;3(8):486-98. doi: 10.1021/cb800051m. Epub 2008 Jul 1. ACS Chem Biol. 2008. PMID: 18590333 Free PMC article.

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