Graham IR - Search Results

1

Human apolipoprotein E expression from mouse skeletal muscle by electrotransfer of nonviral DNA (plasmid) and pseudotyped recombinant adeno-associated virus (AAV2/7).

Evans V, Foster H, Graham IR, Foster K, Athanasopoulos T, Simons JP, Dickson G, Owen JS. Evans V, et al. Among authors: graham ir. Hum Gene Ther. 2008 Jun;19(6):569-78. doi: 10.1089/hum.2007.169. Hum Gene Ther. 2008. PMID: 18578629

2

Codon and mRNA sequence optimization of microdystrophin transgenes improves expression and physiological outcome in dystrophic mdx mice following AAV2/8 gene transfer.

Foster H, Sharp PS, Athanasopoulos T, Trollet C, Graham IR, Foster K, Wells DJ, Dickson G. Foster H, et al. Among authors: graham ir. Mol Ther. 2008 Nov;16(11):1825-32. doi: 10.1038/mt.2008.186. Epub 2008 Sep 2. Mol Ther. 2008. PMID: 18766174 Free article.

3

Preliminary evaluation of a self-complementary AAV2/8 vector for hepatic gene transfer of human apoE3 to inhibit atherosclerotic lesion development in apoE-deficient mice.

Osman E, Evans V, Graham IR, Athanasopoulos T, McIntosh J, Nathwani AC, Simons JP, Dickson G, Owen JS. Osman E, et al. Among authors: graham ir. Atherosclerosis. 2009 May;204(1):121-6. doi: 10.1016/j.atherosclerosis.2008.08.043. Epub 2008 Sep 11. Atherosclerosis. 2009. PMID: 18930458

4

Adeno-associated virus serotypes 7 and 8 outperform serotype 9 in expressing atheroprotective human apoE3 from mouse skeletal muscle.

Evans VC, Graham IR, Athanasopoulos T, Galley DJ, Jackson CL, Simons JP, Dickson G, Owen JS. Evans VC, et al. Among authors: graham ir. Metabolism. 2011 Apr;60(4):491-8. doi: 10.1016/j.metabol.2010.04.015. Epub 2010 May 23. Metabolism. 2011. PMID: 20580777

5

Inhibition of atherosclerosis in apolipoprotein-E-deficient mice following muscle transduction with adeno-associated virus vectors encoding human apolipoprotein-E.

Harris JD, Schepelmann S, Athanasopoulos T, Graham IR, Stannard AK, Mohri Z, Hill V, Hassall DG, Owen JS, Dickson G. Harris JD, et al. Among authors: graham ir. Gene Ther. 2002 Jan;9(1):21-9. doi: 10.1038/sj.gt.3301615. Gene Ther. 2002. PMID: 11850719

6

Recombinant adeno-associated viral (rAAV) vectors as therapeutic tools for Duchenne muscular dystrophy (DMD).

Athanasopoulos T, Graham IR, Foster H, Dickson G. Athanasopoulos T, et al. Among authors: graham ir. Gene Ther. 2004 Oct;11 Suppl 1:S109-21. doi: 10.1038/sj.gt.3302379. Gene Ther. 2004. PMID: 15454965 Review.

7

Failure to generate atheroprotective apolipoprotein AI phenotypes using synthetic RNA/DNA oligonucleotides (chimeraplasts).

Manzano A, Mohri Z, Sperber G, Ogris M, Graham I, Dickson G, Owen JS. Manzano A, et al. J Gene Med. 2003 Sep;5(9):795-802. doi: 10.1002/jgm.403. J Gene Med. 2003. PMID: 12950070

8

Acute regression of advanced and retardation of early aortic atheroma in immunocompetent apolipoprotein-E (apoE) deficient mice by administration of a second generation [E1(-), E3(-), polymerase(-)] adenovirus vector expressing human apoE.

Harris JD, Graham IR, Schepelmann S, Stannard AK, Roberts ML, Hodges BL, Hill V, Amalfitano A, Hassall DG, Owen JS, Dickson G. Harris JD, et al. Among authors: graham ir. Hum Mol Genet. 2002 Jan 1;11(1):43-58. doi: 10.1093/hmg/11.1.43. Hum Mol Genet. 2002. PMID: 11772998

9

Apolipoprotein E delivery by peritoneal implantation of encapsulated recombinant cells improves the hyperlipidaemic profile in apoE-deficient mice.

Tagalakis AD, Diakonov IA, Graham IR, Heald KA, Harris JD, Mulcahy JV, Dickson G, Owen JS. Tagalakis AD, et al. Among authors: graham ir. Biochim Biophys Acta. 2005 Jan 5;1686(3):190-9. doi: 10.1016/j.bbalip.2004.10.001. Biochim Biophys Acta. 2005. PMID: 15629688

10

Adenovirus-based targeting in myoblasts is hampered by nonhomologous vector integration.

Isman O, Roberts ML, Morgan JE, Graham IR, Goldring K, Lawrence-Watt DJ, Lu QL, Dunckley MG, Porter AC, Partridge TA, Dickson G. Isman O, et al. Among authors: graham ir. Hum Gene Ther. 2008 Oct;19(10):1000-8. doi: 10.1089/hum.2008.063. Hum Gene Ther. 2008. PMID: 18788904

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