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Neuromodulatory effect of Gαs- or Gαq-coupled G-protein-coupled receptor on NMDA receptor selectively activates the NMDA receptor/Ca2+/calcineurin/cAMP response element-binding protein-regulated transcriptional coactivator 1 pathway to effectively induce brain-derived neurotrophic factor expression in neurons.
Fukuchi M, Tabuchi A, Kuwana Y, Watanabe S, Inoue M, Takasaki I, Izumi H, Tanaka A, Inoue R, Mori H, Komatsu H, Takemori H, Okuno H, Bito H, Tsuda M. Fukuchi M, et al. Among authors: kuwana y. J Neurosci. 2015 Apr 8;35(14):5606-24. doi: 10.1523/JNEUROSCI.3650-14.2015. J Neurosci. 2015. PMID: 25855176 Free PMC article.
52 results