Mankin H - Search Results

1

CDDO-Me, a synthetic triterpenoid, inhibits expression of IL-6 and Stat3 phosphorylation in multi-drug resistant ovarian cancer cells.

Duan Z, Ames RY, Ryan M, Hornicek FJ, Mankin H, Seiden MV. Duan Z, et al. Among authors: mankin h. Cancer Chemother Pharmacol. 2009 Mar;63(4):681-9. doi: 10.1007/s00280-008-0785-8. Epub 2008 Jun 28. Cancer Chemother Pharmacol. 2009. PMID: 18587580 Free PMC article.

2

Lentiviral short hairpin RNA screen of genes associated with multidrug resistance identifies PRP-4 as a new regulator of chemoresistance in human ovarian cancer.

Duan Z, Weinstein EJ, Ji D, Ames RY, Choy E, Mankin H, Hornicek FJ. Duan Z, et al. Among authors: mankin h. Mol Cancer Ther. 2008 Aug;7(8):2377-85. doi: 10.1158/1535-7163.MCT-08-0316. Epub 2008 Aug 7. Mol Cancer Ther. 2008. PMID: 18687998 Free PMC article.

3

RAIDD expression is impaired in multidrug resistant osteosarcoma cell lines.

Yang C, Hornicek FJ, Wood KB, Schwab JH, Mankin H, Duan Z. Yang C, et al. Among authors: mankin h. Cancer Chemother Pharmacol. 2009 Aug;64(3):607-14. doi: 10.1007/s00280-008-0912-6. Epub 2009 Jan 6. Cancer Chemother Pharmacol. 2009. PMID: 19125251

4

Insulin-like growth factor-I receptor tyrosine kinase inhibitor cyclolignan picropodophyllin inhibits proliferation and induces apoptosis in multidrug resistant osteosarcoma cell lines.

Duan Z, Choy E, Harmon D, Yang C, Ryu K, Schwab J, Mankin H, Hornicek FJ. Duan Z, et al. Among authors: mankin h. Mol Cancer Ther. 2009 Aug;8(8):2122-30. doi: 10.1158/1535-7163.MCT-09-0115. Epub 2009 Jul 28. Mol Cancer Ther. 2009. PMID: 19638450 Free PMC article.

5

Doxorubicin loaded Polymeric Nanoparticulate Delivery System to overcome drug resistance in osteosarcoma.

Susa M, Iyer AK, Ryu K, Hornicek FJ, Mankin H, Amiji MM, Duan Z. Susa M, et al. Among authors: mankin h. BMC Cancer. 2009 Nov 16;9:399. doi: 10.1186/1471-2407-9-399. BMC Cancer. 2009. PMID: 19917123 Free PMC article.

6

Activation of signal transducer and activator of transcription 3 (Stat3) pathway in osteosarcoma cells and overexpression of phosphorylated-Stat3 correlates with poor prognosis.

Ryu K, Choy E, Yang C, Susa M, Hornicek FJ, Mankin H, Duan Z. Ryu K, et al. Among authors: mankin h. J Orthop Res. 2010 Jul;28(7):971-8. doi: 10.1002/jor.21088. J Orthop Res. 2010. PMID: 20063378 Free article.

7

Lentiviral shRNA screen of human kinases identifies PLK1 as a potential therapeutic target for osteosarcoma.

Duan Z, Ji D, Weinstein EJ, Liu X, Susa M, Choy E, Yang C, Mankin H, Hornicek FJ. Duan Z, et al. Among authors: mankin h. Cancer Lett. 2010 Jul 28;293(2):220-9. doi: 10.1016/j.canlet.2010.01.014. Epub 2010 Feb 9. Cancer Lett. 2010. PMID: 20144850

8

Blockage of Stat3 with CDDO-Me inhibits tumor cell growth in chordoma.

Yang C, Hornicek FJ, Wood KB, Schwab JH, Choy E, Mankin H, Duan Z. Yang C, et al. Among authors: mankin h. Spine (Phila Pa 1976). 2010 Aug 15;35(18):1668-75. doi: 10.1097/BRS.0b013e3181c2d2b4. Spine (Phila Pa 1976). 2010. PMID: 20386502

9

Histone deacetylase inhibitor (HDACI) PCI-24781 potentiates cytotoxic effects of doxorubicin in bone sarcoma cells.

Yang C, Choy E, Hornicek FJ, Wood KB, Schwab JH, Liu X, Mankin H, Duan Z. Yang C, et al. Among authors: mankin h. Cancer Chemother Pharmacol. 2011 Feb;67(2):439-46. doi: 10.1007/s00280-010-1344-7. Epub 2010 May 12. Cancer Chemother Pharmacol. 2011. PMID: 20461381

10

Effects of siltuximab on the IL-6-induced signaling pathway in ovarian cancer.

Guo Y, Nemeth J, O'Brien C, Susa M, Liu X, Zhang Z, Choy E, Mankin H, Hornicek F, Duan Z. Guo Y, et al. Among authors: mankin h. Clin Cancer Res. 2010 Dec 1;16(23):5759-69. doi: 10.1158/1078-0432.CCR-10-1095. Epub 2010 Aug 10. Clin Cancer Res. 2010. PMID: 20699329

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