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A model of acquired autoresistance to a potent ErbB2 tyrosine kinase inhibitor and a therapeutic strategy to prevent its onset in breast cancer.
Xia W, Bacus S, Hegde P, Husain I, Strum J, Liu L, Paulazzo G, Lyass L, Trusk P, Hill J, Harris J, Spector NL. Xia W, et al. Among authors: lyass l. Proc Natl Acad Sci U S A. 2006 May 16;103(20):7795-800. doi: 10.1073/pnas.0602468103. Epub 2006 May 8. Proc Natl Acad Sci U S A. 2006. PMID: 16682622 Free PMC article.
A reciprocal tensin-3-cten switch mediates EGF-driven mammary cell migration.
Katz M, Amit I, Citri A, Shay T, Carvalho S, Lavi S, Milanezi F, Lyass L, Amariglio N, Jacob-Hirsch J, Ben-Chetrit N, Tarcic G, Lindzen M, Avraham R, Liao YC, Trusk P, Lyass A, Rechavi G, Spector NL, Lo SH, Schmitt F, Bacus SS, Yarden Y. Katz M, et al. Among authors: lyass l. Nat Cell Biol. 2007 Aug;9(8):961-9. doi: 10.1038/ncb1622. Epub 2007 Jul 22. Nat Cell Biol. 2007. PMID: 17643115
ErbB tyrosine kinases and the two neuregulin families constitute a ligand-receptor network.
Pinkas-Kramarski R, Shelly M, Guarino BC, Wang LM, Lyass L, Alroy I, Alimandi M, Kuo A, Moyer JD, Lavi S, Eisenstein M, Ratzkin BJ, Seger R, Bacus SS, Pierce JH, Andrews GC, Yarden Y. Pinkas-Kramarski R, et al. Among authors: lyass l. Mol Cell Biol. 1998 Oct;18(10):6090-101. doi: 10.1128/MCB.18.10.6090. Mol Cell Biol. 1998. PMID: 9742126 Free PMC article.
21 results