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Mouse development with a single E2F activator.
Tsai SY, Opavsky R, Sharma N, Wu L, Naidu S, Nolan E, Feria-Arias E, Timmers C, Opavska J, de Bruin A, Chong JL, Trikha P, Fernandez SA, Stromberg P, Rosol TJ, Leone G. Tsai SY, et al. Among authors: leone g. Nature. 2008 Aug 28;454(7208):1137-41. doi: 10.1038/nature07066. Epub 2008 Jun 25. Nature. 2008. PMID: 18594513 Free PMC article.
Distinct roles for E2F proteins in cell growth control and apoptosis.
DeGregori J, Leone G, Miron A, Jakoi L, Nevins JR. DeGregori J, et al. Among authors: leone g. Proc Natl Acad Sci U S A. 1997 Jul 8;94(14):7245-50. doi: 10.1073/pnas.94.14.7245. Proc Natl Acad Sci U S A. 1997. PMID: 9207076 Free PMC article.
Myc requires distinct E2F activities to induce S phase and apoptosis.
Leone G, Sears R, Huang E, Rempel R, Nuckolls F, Park CH, Giangrande P, Wu L, Saavedra HI, Field SJ, Thompson MA, Yang H, Fujiwara Y, Greenberg ME, Orkin S, Smith C, Nevins JR. Leone G, et al. Mol Cell. 2001 Jul;8(1):105-13. doi: 10.1016/s1097-2765(01)00275-1. Mol Cell. 2001. PMID: 11511364 Free article.
The E2F1-3 transcription factors are essential for cellular proliferation.
Wu L, Timmers C, Maiti B, Saavedra HI, Sang L, Chong GT, Nuckolls F, Giangrande P, Wright FA, Field SJ, Greenberg ME, Orkin S, Nevins JR, Robinson ML, Leone G. Wu L, et al. Among authors: leone g. Nature. 2001 Nov 22;414(6862):457-62. doi: 10.1038/35106593. Nature. 2001. PMID: 11719808
Extra-embryonic function of Rb is essential for embryonic development and viability.
Wu L, de Bruin A, Saavedra HI, Starovic M, Trimboli A, Yang Y, Opavska J, Wilson P, Thompson JC, Ostrowski MC, Rosol TJ, Woollett LA, Weinstein M, Cross JC, Robinson ML, Leone G. Wu L, et al. Among authors: leone g. Nature. 2003 Feb 27;421(6926):942-7. doi: 10.1038/nature01417. Nature. 2003. PMID: 12607001
Inactivation of E2F3 results in centrosome amplification.
Saavedra HI, Maiti B, Timmers C, Altura R, Tokuyama Y, Fukasawa K, Leone G. Saavedra HI, et al. Among authors: leone g. Cancer Cell. 2003 Apr;3(4):333-46. doi: 10.1016/s1535-6108(03)00083-7. Cancer Cell. 2003. PMID: 12726860 Free PMC article.
1,355 results