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Purification and characterization of the human gamma-secretase complex.
Fraering PC, Ye W, Strub JM, Dolios G, LaVoie MJ, Ostaszewski BL, van Dorsselaer A, Wang R, Selkoe DJ, Wolfe MS. Fraering PC, et al. Among authors: dolios g. Biochemistry. 2004 Aug 3;43(30):9774-89. doi: 10.1021/bi0494976. Biochemistry. 2004. PMID: 15274632
Familial Alzheimer disease-linked presenilin 1 variants enhance production of both Abeta 1-40 and Abeta 1-42 peptides that are only partially sensitive to a potent aspartyl protease transition state inhibitor of "gamma-secretase".
Ikeuchi T, Dolios G, Kim SH, Wang R, Sisodia SS. Ikeuchi T, et al. Among authors: dolios g. J Biol Chem. 2003 Feb 28;278(9):7010-8. doi: 10.1074/jbc.M209252200. Epub 2002 Dec 19. J Biol Chem. 2003. PMID: 12493731 Free article.
54 results