Brecht K - Search Results

1

Interaction with the hERG channel and cytotoxicity of amiodarone and amiodarone analogues.

Waldhauser KM, Brecht K, Hebeisen S, Ha HR, Konrad D, Bur D, Krähenbühl S. Waldhauser KM, et al. Among authors: brecht k. Br J Pharmacol. 2008 Oct;155(4):585-95. doi: 10.1038/bjp.2008.287. Epub 2008 Jul 7. Br J Pharmacol. 2008. PMID: 18604229 Free PMC article.

2

Hepatocellular toxicity and pharmacological effect of amiodarone and amiodarone derivatives.

Waldhauser KM, Török M, Ha HR, Thomet U, Konrad D, Brecht K, Follath F, Krähenbühl S. Waldhauser KM, et al. Among authors: brecht k. J Pharmacol Exp Ther. 2006 Dec;319(3):1413-23. doi: 10.1124/jpet.106.108993. Epub 2006 Sep 13. J Pharmacol Exp Ther. 2006. PMID: 16971508

3

Toxicity of statins on rat skeletal muscle mitochondria.

Kaufmann P, Török M, Zahno A, Waldhauser KM, Brecht K, Krähenbühl S. Kaufmann P, et al. Among authors: brecht k. Cell Mol Life Sci. 2006 Oct;63(19-20):2415-25. doi: 10.1007/s00018-006-6235-z. Cell Mol Life Sci. 2006. PMID: 17013560 Free PMC article.

4

Effect of simvastatin on cholesterol metabolism in C2C12 myotubes and HepG2 cells, and consequences for statin-induced myopathy.

Mullen PJ, Lüscher B, Scharnagl H, Krähenbühl S, Brecht K. Mullen PJ, et al. Among authors: brecht k. Biochem Pharmacol. 2010 Apr 15;79(8):1200-9. doi: 10.1016/j.bcp.2009.12.007. Epub 2009 Dec 14. Biochem Pharmacol. 2010. PMID: 20018177

5

Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro.

Zahno A, Brecht K, Bodmer M, Bur D, Tsakiris DA, Krähenbühl S. Zahno A, et al. Among authors: brecht k. Br J Pharmacol. 2010 Sep;161(2):393-404. doi: 10.1111/j.1476-5381.2010.00881.x. Br J Pharmacol. 2010. PMID: 20735423 Free PMC article.

6

The role of CYP3A4 in amiodarone-associated toxicity on HepG2 cells.

Zahno A, Brecht K, Morand R, Maseneni S, Török M, Lindinger PW, Krähenbühl S. Zahno A, et al. Among authors: brecht k. Biochem Pharmacol. 2011 Feb 1;81(3):432-41. doi: 10.1016/j.bcp.2010.11.002. Epub 2010 Nov 9. Biochem Pharmacol. 2011. PMID: 21070748

7

Susceptibility to simvastatin-induced toxicity is partly determined by mitochondrial respiration and phosphorylation state of Akt.

Mullen PJ, Zahno A, Lindinger P, Maseneni S, Felser A, Krähenbühl S, Brecht K. Mullen PJ, et al. Among authors: brecht k. Biochim Biophys Acta. 2011 Dec;1813(12):2079-87. doi: 10.1016/j.bbamcr.2011.07.019. Epub 2011 Aug 4. Biochim Biophys Acta. 2011. PMID: 21839782 Free article.

8

Toxicity of clopidogrel and ticlopidine on human myeloid progenitor cells: importance of metabolites.

Maseneni S, Donzelli M, Taegtmeyer AB, Brecht K, Krähenbühl S. Maseneni S, et al. Among authors: brecht k. Toxicology. 2012 Sep 28;299(2-3):139-45. doi: 10.1016/j.tox.2012.05.017. Epub 2012 May 28. Toxicology. 2012. PMID: 22651985

9

Toxicity of thienopyridines on human neutrophil granulocytes and lymphocytes.

Maseneni S, Donzelli M, Brecht K, Krähenbühl S. Maseneni S, et al. Among authors: brecht k. Toxicology. 2013 Jun 7;308:11-9. doi: 10.1016/j.tox.2013.03.002. Epub 2013 Mar 15. Toxicology. 2013. PMID: 23499857

10

Hepatocellular toxicity of clopidogrel: mechanisms and risk factors.

Zahno A, Bouitbir J, Maseneni S, Lindinger PW, Brecht K, Krähenbühl S. Zahno A, et al. Among authors: brecht k. Free Radic Biol Med. 2013 Dec;65:208-216. doi: 10.1016/j.freeradbiomed.2013.06.007. Epub 2013 Jun 11. Free Radic Biol Med. 2013. PMID: 23770199

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