O'Shea JJ - Search Results

1

Pesu M, Laurence A, Kishore N, Zwillich SH, Chan G, O'Shea JJ. Pesu M, et al. Immunol Rev. 2008 Jun;223:132-42. doi: 10.1111/j.1600-065X.2008.00644.x. Immunol Rev. 2008. PMID: 18613833 Free PMC article. Review.

2

Interleukin 12 (IL-12) induces tyrosine phosphorylation of JAK2 and TYK2: differential use of Janus family tyrosine kinases by IL-2 and IL-12.

Bacon CM, McVicar DW, Ortaldo JR, Rees RC, O'Shea JJ, Johnston JA. Bacon CM, et al. J Exp Med. 1995 Jan 1;181(1):399-404. doi: 10.1084/jem.181.1.399. J Exp Med. 1995. PMID: 7528775 Free PMC article.

3

Keegan AD, Johnston JA, Tortolani PJ, McReynolds LJ, Kinzer C, O'Shea JJ, Paul WE. Keegan AD, et al. Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7681-5. doi: 10.1073/pnas.92.17.7681. Proc Natl Acad Sci U S A. 1995. PMID: 7544000 Free PMC article.

4

Regulation of JAK3 expression and activation in human B cells and B cell malignancies.

Tortolani PJ, Lal BK, Riva A, Johnston JA, Chen YQ, Reaman GH, Beckwith M, Longo D, Ortaldo JR, Bhatia K, McGrath I, Kehrl J, Tuscano J, McVicar DW, O'Shea JJ. Tortolani PJ, et al. J Immunol. 1995 Dec 1;155(11):5220-6. J Immunol. 1995. PMID: 7594533

5

Thrombopoietin induces tyrosine phosphorylation and activation of the Janus kinase, JAK2.

Tortolani PJ, Johnston JA, Bacon CM, McVicar DW, Shimosaka A, Linnekin D, Longo DL, O'Shea JJ. Tortolani PJ, et al. Blood. 1995 Jun 15;85(12):3444-51. Blood. 1995. PMID: 7780132 Free article.

6

The amino terminus of JAK3 is necessary and sufficient for binding to the common gamma chain and confers the ability to transmit interleukin 2-mediated signals.

Chen M, Cheng A, Chen YQ, Hymel A, Hanson EP, Kimmel L, Minami Y, Taniguchi T, Changelian PS, O'Shea JJ. Chen M, et al. Proc Natl Acad Sci U S A. 1997 Jun 24;94(13):6910-5. doi: 10.1073/pnas.94.13.6910. Proc Natl Acad Sci U S A. 1997. PMID: 9192665 Free PMC article.

7

TGF-beta does not inhibit IL-12- and IL-2-induced activation of Janus kinases and STATs.

Sudarshan C, Galon J, Zhou Y, O'Shea JJ. Sudarshan C, et al. J Immunol. 1999 Mar 1;162(5):2974-81. J Immunol. 1999. PMID: 10072548

8

Janus kinases and their role in growth and disease.

Aringer M, Cheng A, Nelson JW, Chen M, Sudarshan C, Zhou YJ, O'Shea JJ. Aringer M, et al. Life Sci. 1999;64(24):2173-86. doi: 10.1016/s0024-3205(98)00538-4. Life Sci. 1999. PMID: 10374907 Review.

9

Complex effects of naturally occurring mutations in the JAK3 pseudokinase domain: evidence for interactions between the kinase and pseudokinase domains.

Chen M, Cheng A, Candotti F, Zhou YJ, Hymel A, Fasth A, Notarangelo LD, O'Shea JJ. Chen M, et al. Mol Cell Biol. 2000 Feb;20(3):947-56. doi: 10.1128/MCB.20.3.947-956.2000. Mol Cell Biol. 2000. PMID: 10629052 Free PMC article.

10

Inhibition of Th1 immune response by glucocorticoids: dexamethasone selectively inhibits IL-12-induced Stat4 phosphorylation in T lymphocytes.

Franchimont D, Galon J, Gadina M, Visconti R, Zhou Y, Aringer M, Frucht DM, Chrousos GP, O'Shea JJ. Franchimont D, et al. J Immunol. 2000 Feb 15;164(4):1768-74. doi: 10.4049/jimmunol.164.4.1768. J Immunol. 2000. PMID: 10657623

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