Zhang C - Search Results

1

An integrated platform of genomic assays reveals small-molecule bioactivities.

Hoon S, Smith AM, Wallace IM, Suresh S, Miranda M, Fung E, Proctor M, Shokat KM, Zhang C, Davis RW, Giaever G, St Onge RP, Nislow C. Hoon S, et al. Among authors: zhang c. Nat Chem Biol. 2008 Aug;4(8):498-506. doi: 10.1038/nchembio.100. Epub 2008 Jul 11. Nat Chem Biol. 2008. PMID: 18622389

2

Structure-guided development of affinity probes for tyrosine kinases using chemical genetics.

Blair JA, Rauh D, Kung C, Yun CH, Fan QW, Rode H, Zhang C, Eck MJ, Weiss WA, Shokat KM. Blair JA, et al. Among authors: zhang c. Nat Chem Biol. 2007 Apr;3(4):229-38. doi: 10.1038/nchembio866. Epub 2007 Mar 4. Nat Chem Biol. 2007. PMID: 17334377

3

A second-site suppressor strategy for chemical genetic analysis of diverse protein kinases.

Zhang C, Kenski DM, Paulson JL, Bonshtien A, Sessa G, Cross JV, Templeton DJ, Shokat KM. Zhang C, et al. Nat Methods. 2005 Jun;2(6):435-41. doi: 10.1038/nmeth764. Nat Methods. 2005. PMID: 15908922

4

Design and use of analog-sensitive protein kinases.

Blethrow J, Zhang C, Shokat KM, Weiss EL. Blethrow J, et al. Among authors: zhang c. Curr Protoc Mol Biol. 2004 May;Chapter 18:Unit 18.11. doi: 10.1002/0471142727.mb1811s66. Curr Protoc Mol Biol. 2004. PMID: 18265343

5

Inhibitor hijacking of Akt activation.

Okuzumi T, Fiedler D, Zhang C, Gray DC, Aizenstein B, Hoffman R, Shokat KM. Okuzumi T, et al. Among authors: zhang c. Nat Chem Biol. 2009 Jul;5(7):484-93. doi: 10.1038/nchembio.183. Epub 2009 May 24. Nat Chem Biol. 2009. PMID: 19465931 Free PMC article.

6

Structure-guided inhibitor design expands the scope of analog-sensitive kinase technology.

Zhang C, Lopez MS, Dar AC, Ladow E, Finkbeiner S, Yun CH, Eck MJ, Shokat KM. Zhang C, et al. ACS Chem Biol. 2013 Sep 20;8(9):1931-8. doi: 10.1021/cb400376p. Epub 2013 Jul 23. ACS Chem Biol. 2013. PMID: 23841803 Free PMC article.

7

Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling.

Tan YX, Manz BN, Freedman TS, Zhang C, Shokat KM, Weiss A. Tan YX, et al. Among authors: zhang c. Nat Immunol. 2014 Feb;15(2):186-94. doi: 10.1038/ni.2772. Epub 2013 Dec 8. Nat Immunol. 2014. PMID: 24317039 Free PMC article.

8

Chemical genetic blockade of transformation reveals dependence on aberrant oncogenic signaling.

Fan QW, Zhang C, Shokat KM, Weiss WA. Fan QW, et al. Among authors: zhang c. Curr Biol. 2002 Aug 20;12(16):1386-94. doi: 10.1016/s0960-9822(02)01070-9. Curr Biol. 2002. PMID: 12194819 Free article.

9

A coupled chemical-genetic and bioinformatic approach to Polo-like kinase pathway exploration.

Snead JL, Sullivan M, Lowery DM, Cohen MS, Zhang C, Randle DH, Taunton J, Yaffe MB, Morgan DO, Shokat KM. Snead JL, et al. Among authors: zhang c. Chem Biol. 2007 Nov;14(11):1261-72. doi: 10.1016/j.chembiol.2007.09.011. Chem Biol. 2007. PMID: 18022565 Free PMC article.

10

The unfolded protein response signals through high-order assembly of Ire1.

Korennykh AV, Egea PF, Korostelev AA, Finer-Moore J, Zhang C, Shokat KM, Stroud RM, Walter P. Korennykh AV, et al. Among authors: zhang c. Nature. 2009 Feb 5;457(7230):687-93. doi: 10.1038/nature07661. Epub 2008 Dec 14. Nature. 2009. PMID: 19079236 Free PMC article.

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