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A diarylquinoline drug active on the ATP synthase of Mycobacterium tuberculosis.
Andries K, Verhasselt P, Guillemont J, Göhlmann HW, Neefs JM, Winkler H, Van Gestel J, Timmerman P, Zhu M, Lee E, Williams P, de Chaffoy D, Huitric E, Hoffner S, Cambau E, Truffot-Pernot C, Lounis N, Jarlier V. Andries K, et al. Science. 2005 Jan 14;307(5707):223-7. doi: 10.1126/science.1106753. Epub 2004 Dec 9. Science. 2005. PMID: 15591164 Clinical Trial.
Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome.
Aerssens J, Camilleri M, Talloen W, Thielemans L, Göhlmann HW, Van Den Wyngaert I, Thielemans T, De Hoogt R, Andrews CN, Bharucha AE, Carlson PJ, Busciglio I, Burton DD, Smyrk T, Urrutia R, Coulie B. Aerssens J, et al. Clin Gastroenterol Hepatol. 2008 Feb;6(2):194-205. doi: 10.1016/j.cgh.2007.11.012. Clin Gastroenterol Hepatol. 2008. PMID: 18237869 Free PMC article.
Integrating High-Dimensional Transcriptomics and Image Analysis Tools into Early Safety Screening: Proof of Concept for a New Early Drug Development Strategy.
Verbist BM, Verheyen GR, Vervoort L, Crabbe M, Beerens D, Bosmans C, Jaensch S, Osselaer S, Talloen W, Van den Wyngaert I, Van Hecke G, Wuyts D; QSTAR Consortium; Van Goethem F, Göhlmann HW. Verbist BM, et al. Chem Res Toxicol. 2015 Oct 19;28(10):1914-25. doi: 10.1021/acs.chemrestox.5b00103. Epub 2015 Sep 15. Chem Res Toxicol. 2015. PMID: 26313431 Free article.
Tales of 1,008 small molecules: phenomic profiling through live-cell imaging in a panel of reporter cell lines.
Cox MJ, Jaensch S, Van de Waeter J, Cougnaud L, Seynaeve D, Benalla S, Koo SJ, Van Den Wyngaert I, Neefs JM, Malkov D, Bittremieux M, Steemans M, Peeters PJ, Wegner JK, Ceulemans H, Gustin E, Chong YT, Göhlmann HWH. Cox MJ, et al. Among authors: gohlmann hwh. Sci Rep. 2020 Aug 6;10(1):13262. doi: 10.1038/s41598-020-69354-8. Sci Rep. 2020. PMID: 32764586 Free PMC article.
39 results