Medeiros DM - Search Results

1

Transcriptional coactivators PGC-1alpha and PGC-lbeta control overlapping programs required for perinatal maturation of the heart.

Lai L, Leone TC, Zechner C, Schaeffer PJ, Kelly SM, Flanagan DP, Medeiros DM, Kovacs A, Kelly DP. Lai L, et al. Among authors: medeiros dm. Genes Dev. 2008 Jul 15;22(14):1948-61. doi: 10.1101/gad.1661708. Genes Dev. 2008. PMID: 18628400 Free PMC article.

2

PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis.

Leone TC, Lehman JJ, Finck BN, Schaeffer PJ, Wende AR, Boudina S, Courtois M, Wozniak DF, Sambandam N, Bernal-Mizrachi C, Chen Z, Holloszy JO, Medeiros DM, Schmidt RE, Saffitz JE, Abel ED, Semenkovich CF, Kelly DP. Leone TC, et al. Among authors: medeiros dm. PLoS Biol. 2005 Apr;3(4):e101. doi: 10.1371/journal.pbio.0030101. Epub 2005 Mar 15. PLoS Biol. 2005. PMID: 15760270 Free PMC article.

3

The transcriptional coactivators, PGC-1α and β, cooperate to maintain cardiac mitochondrial function during the early stages of insulin resistance.

Mitra R, Nogee DP, Zechner JF, Yea K, Gierasch CM, Kovacs A, Medeiros DM, Kelly DP, Duncan JG. Mitra R, et al. Among authors: medeiros dm. J Mol Cell Cardiol. 2012 Mar;52(3):701-10. doi: 10.1016/j.yjmcc.2011.10.010. Epub 2011 Oct 20. J Mol Cell Cardiol. 2012. PMID: 22080103 Free PMC article.

4

Cardiac-specific induction of the transcriptional coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha promotes mitochondrial biogenesis and reversible cardiomyopathy in a developmental stage-dependent manner.

Russell LK, Mansfield CM, Lehman JJ, Kovacs A, Courtois M, Saffitz JE, Medeiros DM, Valencik ML, McDonald JA, Kelly DP. Russell LK, et al. Among authors: medeiros dm. Circ Res. 2004 Mar 5;94(4):525-33. doi: 10.1161/01.RES.0000117088.36577.EB. Epub 2004 Jan 15. Circ Res. 2004. PMID: 14726475

5

Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.

Duncan JG, Fong JL, Medeiros DM, Finck BN, Kelly DP. Duncan JG, et al. Among authors: medeiros dm. Circulation. 2007 Feb 20;115(7):909-17. doi: 10.1161/CIRCULATIONAHA.106.662296. Epub 2007 Jan 29. Circulation. 2007. PMID: 17261654 Free PMC article.

6

Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis.

Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP. Lehman JJ, et al. Among authors: medeiros dm. J Clin Invest. 2000 Oct;106(7):847-56. doi: 10.1172/JCI10268. J Clin Invest. 2000. PMID: 11018072 Free PMC article.

7

Mitochondrial transcription factor A is increased but expression of ATP synthase beta subunit and medium-chain acyl-CoA dehydrogenase genes are decreased in hearts of copper-deficient rats.

Mao S, Leone TC, Kelly DP, Medeiros DM. Mao S, et al. Among authors: medeiros dm. J Nutr. 2000 Sep;130(9):2143-50. doi: 10.1093/jn/130.9.2143. J Nutr. 2000. PMID: 10958805

8

Mitochondrial and sarcoplasmic protein changes in hearts from copper-deficient rats: up-regulation of PGC-1alpha transcript and protein as a cause for mitochondrial biogenesis in copper deficiency.

Medeiros DM, Jiang Y, Klaahsen D, Lin D. Medeiros DM, et al. J Nutr Biochem. 2009 Oct;20(10):823-30. doi: 10.1016/j.jnutbio.2008.08.001. Epub 2008 Nov 6. J Nutr Biochem. 2009. PMID: 18993053 Free article.

9

Tempol prevents impairment of the endothelial cell wound healing response caused by ionising radiation.

Braunhut SJ, Medeiros D, Lai L, Bump EA. Braunhut SJ, et al. Br J Cancer Suppl. 1996 Jul;27:S157-60. Br J Cancer Suppl. 1996. PMID: 8763870 Free PMC article.

10

Marginal copper and high fat diet produce alterations in electrocardiograms and cardiac ultrastructure in male rats.

Mao S, Medeiros DM, Hamlin RL. Mao S, et al. Among authors: medeiros dm. Nutrition. 1999 Nov-Dec;15(11-12):890-8. doi: 10.1016/s0899-9007(99)00156-2. Nutrition. 1999. PMID: 10575667

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