Clotet-Codina I - Search Results

1

5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile.

Nawrozkij MB, Rotili D, Tarantino D, Botta G, Eremiychuk AS, Musmuca I, Ragno R, Samuele A, Zanoli S, Armand-Ugón M, Clotet-Codina I, Novakov IA, Orlinson BS, Maga G, Esté JA, Artico M, Mai A. Nawrozkij MB, et al. Among authors: clotet codina i. J Med Chem. 2008 Aug 14;51(15):4641-52. doi: 10.1021/jm800340w. Epub 2008 Jul 17. J Med Chem. 2008. PMID: 18630898

2

Synthesis and biological properties of novel 2-aminopyrimidin-4(3H)-ones highly potent against HIV-1 mutant strains.

Mai A, Artico M, Rotili D, Tarantino D, Clotet-Codina I, Armand-Ugón M, Ragno R, Simeoni S, Sbardella G, Nawrozkij MB, Samuele A, Maga G, Esté JA. Mai A, et al. Among authors: clotet codina i. J Med Chem. 2007 Nov 1;50(22):5412-24. doi: 10.1021/jm070811e. Epub 2007 Oct 2. J Med Chem. 2007. PMID: 17910429

3

Parallel solution-phase and microwave-assisted synthesis of new S-DABO derivatives endowed with subnanomolar anti-HIV-1 activity.

Manetti F, Esté JA, Clotet-Codina I, Armand-Ugón M, Maga G, Crespan E, Cancio R, Mugnaini C, Bernardini C, Togninelli A, Carmi C, Alongi M, Petricci E, Massa S, Corelli F, Botta M. Manetti F, et al. J Med Chem. 2005 Dec 15;48(25):8000-8. doi: 10.1021/jm050744t. J Med Chem. 2005. PMID: 16335924

4

Synthesis and biological investigation of S-aryl-S-DABO derivatives as HIV-1 inhibitors.

Mugnaini C, Manetti F, Esté JA, Clotet-Codina I, Maga G, Cancio R, Botta M, Corelli F. Mugnaini C, et al. Bioorg Med Chem Lett. 2006 Jul 1;16(13):3541-4. doi: 10.1016/j.bmcl.2006.03.080. Epub 2006 Apr 18. Bioorg Med Chem Lett. 2006. PMID: 16621553

5

Dihydro-alkylthio-benzyl-oxopyrimidines as inhibitors of reverse transcriptase: synthesis and rationalization of the biological data on both wild-type enzyme and relevant clinical mutants.

Mugnaini C, Alongi M, Togninelli A, Gevariya H, Brizzi A, Manetti F, Bernardini C, Angeli L, Tafi A, Bellucci L, Corelli F, Massa S, Maga G, Samuele A, Facchini M, Clotet-Codina I, Armand-Ugón M, Esté JA, Botta M. Mugnaini C, et al. Among authors: clotet codina i. J Med Chem. 2007 Dec 27;50(26):6580-95. doi: 10.1021/jm0708230. Epub 2007 Dec 6. J Med Chem. 2007. PMID: 18052319

6

Recent advances in combinatorial chemistry applied to development of anti-HIV drugs.

Pettersson S, Clotet-Codina I, Esté JA, Borrell JI, Teixidó J. Pettersson S, et al. Mini Rev Med Chem. 2006 Jan;6(1):91-108. doi: 10.2174/138955706775197820. Mini Rev Med Chem. 2006. PMID: 16457634 Review.

7

A multidisciplinary approach for the identification of novel HIV-1 non-nucleoside reverse transcriptase inhibitors: S-DABOCs and DAVPs.

Radi M, Falciani C, Contemori L, Petricci E, Maga G, Samuele A, Zanoli S, Terrazas M, Castria M, Togninelli A, Esté JA, Clotet-Codina I, Armand-Ugón M, Botta M. Radi M, et al. Among authors: clotet codina i. ChemMedChem. 2008 Apr;3(4):573-93. doi: 10.1002/cmdc.200700198. ChemMedChem. 2008. PMID: 18081133

8

Search for alpha-glucosidase inhibitors: new N-substituted valienamine and conduramine F-1 derivatives.

Łysek R, Schütz C, Favre S, O'Sullivan AC, Pillonel C, Krülle T, Jung PM, Clotet-Codina I, Esté JA, Vogel P. Łysek R, et al. Bioorg Med Chem. 2006 Sep 15;14(18):6255-82. doi: 10.1016/j.bmc.2006.05.080. Epub 2006 Jun 22. Bioorg Med Chem. 2006. PMID: 16797996

9

Slow-, tight-binding HIV-1 reverse transcriptase non-nucleoside inhibitors highly active against drug-resistant mutants.

Cancio R, Mai A, Rotili D, Artico M, Sbardella G, Clotet-Codina I, Esté JA, Crespan E, Zanoli S, Hübscher U, Spadari S, Maga G. Cancio R, et al. ChemMedChem. 2007 Apr;2(4):445-8. doi: 10.1002/cmdc.200600310. ChemMedChem. 2007. PMID: 17323401 No abstract available.

10

A combination of molecular dynamics and docking calculations to explore the binding mode of ADS-J1, a polyanionic compound endowed with anti-HIV-1 activity.

Manetti F, Tintori C, Armand-Ugón M, Clotet-Codina I, Massa S, Ragno R, Esté JA, Botta M. Manetti F, et al. J Chem Inf Model. 2006 May-Jun;46(3):1344-51. doi: 10.1021/ci050414h. J Chem Inf Model. 2006. PMID: 16711753

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