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5-Alkyl-6-benzyl-2-(2-oxo-2-phenylethylsulfanyl)pyrimidin-4(3H)-ones, a series of anti-HIV-1 agents of the dihydro-alkoxy-benzyl-oxopyrimidine family with peculiar structure-activity relationship profile.
Nawrozkij MB, Rotili D, Tarantino D, Botta G, Eremiychuk AS, Musmuca I, Ragno R, Samuele A, Zanoli S, Armand-Ugón M, Clotet-Codina I, Novakov IA, Orlinson BS, Maga G, Esté JA, Artico M, Mai A. Nawrozkij MB, et al. Among authors: novakov ia. J Med Chem. 2008 Aug 14;51(15):4641-52. doi: 10.1021/jm800340w. Epub 2008 Jul 17. J Med Chem. 2008. PMID: 18630898
Synthesis and assessment of 4-aminotetrahydroquinazoline derivatives as tick-borne encephalitis virus reproduction inhibitors.
Sedenkova KN, Dueva EV, Averina EB, Grishin YK, Osolodkin DI, Kozlovskaya LI, Palyulin VA, Savelyev EN, Orlinson BS, Novakov IA, Butov GM, Kuznetsova TS, Karganova GG, Zefirov NS. Sedenkova KN, et al. Among authors: novakov ia. Org Biomol Chem. 2015 Mar 21;13(11):3406-15. doi: 10.1039/c4ob02649g. Org Biomol Chem. 2015. PMID: 25661883