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The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the "Fountain of Youth" to mediate healthful aging.
Haussler MR, Haussler CA, Whitfield GK, Hsieh JC, Thompson PD, Barthel TK, Bartik L, Egan JB, Wu Y, Kubicek JL, Lowmiller CL, Moffet EW, Forster RE, Jurutka PW. Haussler MR, et al. Among authors: egan jb. J Steroid Biochem Mol Biol. 2010 Jul;121(1-2):88-97. doi: 10.1016/j.jsbmb.2010.03.019. Epub 2010 Mar 20. J Steroid Biochem Mol Biol. 2010. PMID: 20227497 Free PMC article.
Exome Sequencing Identifies Carriers of the Autosomal Dominant Cancer Predisposition Disorders Beyond Current Practice Guideline Recommendations.
Samadder NJ, Gay E, Lindpere V, Bublitz ML, Bandel LA, Armasu SM, Vierkant RA, Ferber MJ, Klee EW, Larson NB, Kruisselbrink TM, Egan JB, Kemppainen JL, Bidwell JS, Anderson JL, McAllister TM, Walker TS, Kunze KL, Golafshar MA, Klint MA, Presutti RJ, Bobo WV, Sekulic A, Summer-Bolster JM, Willman CL, Lazaridis KN. Samadder NJ, et al. Among authors: egan jb. JCO Precis Oncol. 2024 Jul;8:e2400106. doi: 10.1200/PO.24.00106. JCO Precis Oncol. 2024. PMID: 39013133
Genome-wide analysis of aberrant position and sequence of plasma DNA fragment ends in patients with cancer.
Budhraja KK, McDonald BR, Stephens MD, Contente-Cuomo T, Markus H, Farooq M, Favaro PF, Connor S, Byron SA, Egan JB, Ernst B, McDaniel TK, Sekulic A, Tran NL, Prados MD, Borad MJ, Berens ME, Pockaj BA, LoRusso PM, Bryce A, Trent JM, Murtaza M. Budhraja KK, et al. Among authors: egan jb. Sci Transl Med. 2023 Jan 11;15(678):eabm6863. doi: 10.1126/scitranslmed.abm6863. Epub 2023 Jan 11. Sci Transl Med. 2023. PMID: 36630480 Free PMC article.
Synergistic combination of cytotoxic chemotherapy and cyclin-dependent kinase 4/6 inhibitors in biliary tract cancers.
Arora M, Bogenberger JM, Abdelrahman AM, Yonkus J, Alva-Ruiz R, Leiting JL, Chen X, Serrano Uson Junior PL, Dumbauld CR, Baker AT, Gamb SI, Egan JB, Zhou Y, Nagalo BM, Meurice N, Eskelinen EL, Salomao MA, Kosiorek HE, Braggio E, Barrett MT, Buetow KH, Sonbol MB, Mansfield AS, Roberts LR, Bekaii-Saab TS, Ahn DH, Truty MJ, Borad MJ. Arora M, et al. Among authors: egan jb. Hepatology. 2022 Jan;75(1):43-58. doi: 10.1002/hep.32102. Epub 2021 Dec 12. Hepatology. 2022. PMID: 34407567
Differential impact of tumor suppressor gene (TP53, PTEN, RB1) alterations and treatment outcomes in metastatic, hormone-sensitive prostate cancer.
Velez MG, Kosiorek HE, Egan JB, McNatty AL, Riaz IB, Hwang SR, Stewart GA, Ho TH, Moore CN, Singh P, Sharpsten RK, Costello BA, Bryce AH. Velez MG, et al. Among authors: egan jb. Prostate Cancer Prostatic Dis. 2022 Sep;25(3):479-483. doi: 10.1038/s41391-021-00430-4. Epub 2021 Jul 22. Prostate Cancer Prostatic Dis. 2022. PMID: 34294873 Free PMC article.
LPCAT1-TERT fusions are uniquely recurrent in epithelioid trophoblastic tumors and positively regulate cell growth.
Oliver GR, Marcano-Bonilla S, Quist J, Tolosa EJ, Iguchi E, Swanson AA, Hoppman NL, Schwab T, Sigafoos A, Prodduturi N, Voss JS, Knight SM, Zhang J, Fadra N, Urrutia R, Zimmerman M, Egan JB, Bilyeu AG, Jen J, Veras E, Al-Safi R, Block M, Kerr S, Fernandez-Zapico ME, Schoolmeester JK, Klee EW. Oliver GR, et al. Among authors: egan jb. PLoS One. 2021 May 25;16(5):e0250518. doi: 10.1371/journal.pone.0250518. eCollection 2021. PLoS One. 2021. PMID: 34033669 Free PMC article.
117 results