Chang TH - Search Results

1

Virus infection triggers SUMOylation of IRF3 and IRF7, leading to the negative regulation of type I interferon gene expression.

Kubota T, Matsuoka M, Chang TH, Tailor P, Sasaki T, Tashiro M, Kato A, Ozato K. Kubota T, et al. Among authors: chang th. J Biol Chem. 2008 Sep 12;283(37):25660-25670. doi: 10.1074/jbc.M804479200. Epub 2008 Jul 17. J Biol Chem. 2008. PMID: 18635538 Free PMC article.

2

Tripartite Motif (TRIM) 12c, a Mouse Homolog of TRIM5, Is a Ubiquitin Ligase That Stimulates Type I IFN and NF-κB Pathways along with TNFR-Associated Factor 6.

Chang TH, Yoshimi R, Ozato K. Chang TH, et al. J Immunol. 2015 Dec 1;195(11):5367-79. doi: 10.4049/jimmunol.1402064. Epub 2015 Oct 26. J Immunol. 2015. PMID: 26503954 Free PMC article.

3

Ebolavirus VP35 interacts with the cytoplasmic dynein light chain 8.

Kubota T, Matsuoka M, Chang TH, Bray M, Jones S, Tashiro M, Kato A, Ozato K. Kubota T, et al. Among authors: chang th. J Virol. 2009 Jul;83(13):6952-6. doi: 10.1128/JVI.00480-09. Epub 2009 Apr 29. J Virol. 2009. PMID: 19403681 Free PMC article.

4

Gene disruption study reveals a nonredundant role for TRIM21/Ro52 in NF-kappaB-dependent cytokine expression in fibroblasts.

Yoshimi R, Chang TH, Wang H, Atsumi T, Morse HC 3rd, Ozato K. Yoshimi R, et al. Among authors: chang th. J Immunol. 2009 Jun 15;182(12):7527-38. doi: 10.4049/jimmunol.0804121. J Immunol. 2009. PMID: 19494276 Free PMC article.

5

Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery.

Chang TH, Kubota T, Matsuoka M, Jones S, Bradfute SB, Bray M, Ozato K. Chang TH, et al. PLoS Pathog. 2009 Jun;5(6):e1000493. doi: 10.1371/journal.ppat.1000493. Epub 2009 Jun 26. PLoS Pathog. 2009. PMID: 19557165 Free PMC article.

6

Virus-induced differential expression of nuclear receptors and coregulators in dendritic cells: implication to interferon production.

Ng SS, Chang TH, Tailor P, Ozato K, Kino T. Ng SS, et al. Among authors: chang th. FEBS Lett. 2011 May 6;585(9):1331-7. doi: 10.1016/j.febslet.2011.04.001. Epub 2011 Apr 7. FEBS Lett. 2011. PMID: 21492741 Free PMC article.

7

The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation.

Chang TH, Xu S, Tailor P, Kanno T, Ozato K. Chang TH, et al. J Immunol. 2012 Oct 1;189(7):3548-56. doi: 10.4049/jimmunol.1201104. Epub 2012 Aug 31. J Immunol. 2012. PMID: 22942423 Free PMC article.

8

Functionally distinct effects of the C-terminal regions of IKKε and TBK1 on type I IFN production.

Nakatsu Y, Matsuoka M, Chang TH, Otsuki N, Noda M, Kimura H, Sakai K, Kato H, Takeda M, Kubota T. Nakatsu Y, et al. Among authors: chang th. PLoS One. 2014 Apr 10;9(4):e94999. doi: 10.1371/journal.pone.0094999. eCollection 2014. PLoS One. 2014. PMID: 24722368 Free PMC article.

9

TRIM family proteins and their emerging roles in innate immunity.

Ozato K, Shin DM, Chang TH, Morse HC 3rd. Ozato K, et al. Among authors: chang th. Nat Rev Immunol. 2008 Nov;8(11):849-60. doi: 10.1038/nri2413. Nat Rev Immunol. 2008. PMID: 18836477 Free PMC article. Review.

10

Dengue virus serotype 2 blocks extracellular signal-regulated kinase and nuclear factor-κB activation to downregulate cytokine production.

Chang TH, Chen SR, Yu CY, Lin YS, Chen YS, Kubota T, Matsuoka M, Lin YL. Chang TH, et al. PLoS One. 2012;7(8):e41635. doi: 10.1371/journal.pone.0041635. Epub 2012 Aug 22. PLoS One. 2012. PMID: 22927911 Free PMC article.

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