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Pediatric mastocytosis-associated KIT extracellular domain mutations exhibit different functional and signaling properties compared with KIT-phosphotransferase domain mutations.
Yang Y, Létard S, Borge L, Chaix A, Hanssens K, Lopez S, Vita M, Finetti P, Birnbaum D, Bertucci F, Gomez S, de Sepulveda P, Dubreuil P. Yang Y, et al. Blood. 2010 Aug 19;116(7):1114-23. doi: 10.1182/blood-2009-06-226027. Epub 2010 May 18. Blood. 2010. PMID: 20484085 Free article.
Rapamycin inhibits growth and survival of D816V-mutated c-kit mast cells.
Gabillot-Carré M, Lepelletier Y, Humbert M, de Sepuvelda P, Hamouda NB, Zappulla JP, Liblau R, Ribadeau-Dumas A, Machavoine F, Letard S, Baude C, Hermant A, Yang Y, Vargaftig J, Bodemer C, Morelon E, Lortholary O, Recher C, Laurent G, Dy M, Arock M, Dubreuil P, Hermine O. Gabillot-Carré M, et al. Among authors: yang y. Blood. 2006 Aug 1;108(3):1065-72. doi: 10.1182/blood-2005-06-2433. Epub 2006 Apr 4. Blood. 2006. PMID: 16597595 Free article.
Phenotypic and genotypic characteristics of mastocytosis according to the age of onset.
Lanternier F, Cohen-Akenine A, Palmerini F, Feger F, Yang Y, Zermati Y, Barète S, Sans B, Baude C, Ghez D, Suarez F, Delarue R, Casassus P, Bodemer C, Catteau A, Soppelsa F, Hanssens K, Arock M, Sobol H, Fraitag S, Canioni D, Moussy A, Launay JM, Dubreuil P, Hermine O, Lortholary O; AFIRMM network. Lanternier F, et al. Among authors: yang y. PLoS One. 2008 Apr 9;3(4):e1906. doi: 10.1371/journal.pone.0001906. PLoS One. 2008. PMID: 18404201 Free PMC article.
Pediatric mastocytosis is a clonal disease associated with D816V and other activating c-KIT mutations.
Bodemer C, Hermine O, Palmérini F, Yang Y, Grandpeix-Guyodo C, Leventhal PS, Hadj-Rabia S, Nasca L, Georgin-Lavialle S, Cohen-Akenine A, Launay JM, Barete S, Feger F, Arock M, Catteau B, Sans B, Stalder JF, Skowron F, Thomas L, Lorette G, Plantin P, Bordigoni P, Lortholary O, de Prost Y, Moussy A, Sobol H, Dubreuil P. Bodemer C, et al. Among authors: yang y. J Invest Dermatol. 2010 Mar;130(3):804-15. doi: 10.1038/jid.2009.281. Epub 2009 Oct 29. J Invest Dermatol. 2010. PMID: 19865100 Free article.
Mast cell leukemia: identification of a new c-Kit mutation, dup(501-502), and response to masitinib, a c-Kit tyrosine kinase inhibitor.
Georgin-Lavialle S, Lhermitte L, Suarez F, Yang Y, Letard S, Hanssens K, Feger F, Renand A, Brouze C, Canioni D, Asnafi V, Chandesris MO, Aouba A, Gineste P, Macintyre E, Mansfield CD, Moussy A, Lepelletier Y, Dubreuil P, Hermine O. Georgin-Lavialle S, et al. Among authors: yang y. Eur J Haematol. 2012 Jul;89(1):47-52. doi: 10.1111/j.1600-0609.2012.01761.x. Epub 2012 Apr 28. Eur J Haematol. 2012. PMID: 22324351
Case-control cohort study of patients' perceptions of disability in mastocytosis.
Hermine O, Lortholary O, Leventhal PS, Catteau A, Soppelsa F, Baude C, Cohen-Akenine A, Palmérini F, Hanssens K, Yang Y, Sobol H, Fraytag S, Ghez D, Suarez F, Barete S, Casassus P, Sans B, Arock M, Kinet JP, Dubreuil P, Moussy A. Hermine O, et al. Among authors: yang y. PLoS One. 2008 May 28;3(5):e2266. doi: 10.1371/journal.pone.0002266. PLoS One. 2008. PMID: 18509466 Free PMC article.
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