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Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.
Ananyeva NM, Makogonenko YM, Sarafanov AG, Pechik IV, Gorlatova N, Radtke KP, Shima M, Saenko EL. Ananyeva NM, et al. Among authors: saenko el. Blood Coagul Fibrinolysis. 2008 Sep;19(6):543-55. doi: 10.1097/MBC.0b013e3283068859. Blood Coagul Fibrinolysis. 2008. PMID: 18685438
The binding sites for the very low density lipoprotein receptor and low-density lipoprotein receptor-related protein are shared within coagulation factor VIII.
Ananyeva NM, Makogonenko YM, Kouiavskaia DV, Ruiz J, Limburg V, Meijer AB, Khrenov AV, Shima M, Strickland DK, Saenko EL. Ananyeva NM, et al. Among authors: saenko el. Blood Coagul Fibrinolysis. 2008 Mar;19(2):166-77. doi: 10.1097/MBC.0b013e3282f5457b. Blood Coagul Fibrinolysis. 2008. PMID: 18277139
105 results