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Page 1
Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance.
McCubrey JA, Abrams SL, Ligresti G, Misaghian N, Wong EW, Steelman LS, Bäsecke J, Troppmair J, Libra M, Nicoletti F, Molton S, McMahon M, Evangelisti C, Martelli AM. McCubrey JA, et al. Among authors: misaghian n. Leukemia. 2008 Nov;22(11):2080-90. doi: 10.1038/leu.2008.207. Epub 2008 Aug 7. Leukemia. 2008. PMID: 18685611
Targeting the leukemic stem cell: the Holy Grail of leukemia therapy.
Misaghian N, Ligresti G, Steelman LS, Bertrand FE, Bäsecke J, Libra M, Nicoletti F, Stivala F, Milella M, Tafuri A, Cervello M, Martelli AM, McCubrey JA. Misaghian N, et al. Leukemia. 2009 Jan;23(1):25-42. doi: 10.1038/leu.2008.246. Epub 2008 Sep 18. Leukemia. 2009. PMID: 18800146 Free PMC article. Review.
Alteration of Akt activity increases chemotherapeutic drug and hormonal resistance in breast cancer yet confers an achilles heel by sensitization to targeted therapy.
McCubrey JA, Sokolosky ML, Lehmann BD, Taylor JR, Navolanic PM, Chappell WH, Abrams SL, Stadelman KM, Wong EW, Misaghian N, Horn S, Bäsecke J, Libra M, Stivala F, Ligresti G, Tafuri A, Milella M, Zarzycki M, Dzugaj A, Chiarini F, Evangelisti C, Martelli AM, Terrian DM, Franklin RA, Steelman LS. McCubrey JA, et al. Among authors: misaghian n. Adv Enzyme Regul. 2008;48:113-35. doi: 10.1016/j.advenzreg.2008.02.006. Epub 2008 Feb 21. Adv Enzyme Regul. 2008. PMID: 18423407 Free PMC article.
Targeting the cancer initiating cell: the ultimate target for cancer therapy.
McCubrey JA, Steelman LS, Abrams SL, Misaghian N, Chappell WH, Basecke J, Nicoletti F, Libra M, Ligresti G, Stivala F, Maksimovic-Ivanic D, Mijatovic S, Montalto G, Cervello M, Laidler P, Bonati A, Evangelisti C, Cocco L, Martelli AM. McCubrey JA, et al. Among authors: misaghian n. Curr Pharm Des. 2012;18(13):1784-95. doi: 10.2174/138161212799859701. Curr Pharm Des. 2012. PMID: 22394167 Review.