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Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo.
Wu W, Ye H, Wan L, Han X, Wang G, Hu J, Tang M, Duan X, Fan Y, He S, Huang L, Pei H, Wang X, Li X, Xie C, Zhang R, Yuan Z, Mao Y, Wei Y, Chen L. Wu W, et al. Among authors: fan y. Carcinogenesis. 2013 Jul;34(7):1636-43. doi: 10.1093/carcin/bgt087. Epub 2013 Mar 7. Carcinogenesis. 2013. PMID: 23471882
Parathyroid Hormone Directs Bone Marrow Mesenchymal Cell Fate.
Fan Y, Hanai JI, Le PT, Bi R, Maridas D, DeMambro V, Figueroa CA, Kir S, Zhou X, Mannstadt M, Baron R, Bronson RT, Horowitz MC, Wu JY, Bilezikian JP, Dempster DW, Rosen CJ, Lanske B. Fan Y, et al. Cell Metab. 2017 Mar 7;25(3):661-672. doi: 10.1016/j.cmet.2017.01.001. Epub 2017 Feb 2. Cell Metab. 2017. PMID: 28162969 Free PMC article.
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