Shearer GM - Search Results

1

HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation.

Boasso A, Hardy AW, Anderson SA, Dolan MJ, Shearer GM. Boasso A, et al. Among authors: shearer gm. PLoS One. 2008 Aug 13;3(8):e2961. doi: 10.1371/journal.pone.0002961. PLoS One. 2008. PMID: 18698365 Free PMC article.

2

CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis.

Herbeuval JP, Grivel JC, Boasso A, Hardy AW, Chougnet C, Dolan MJ, Yagita H, Lifson JD, Shearer GM. Herbeuval JP, et al. Among authors: shearer gm. Blood. 2005 Nov 15;106(10):3524-31. doi: 10.1182/blood-2005-03-1243. Epub 2005 Jul 26. Blood. 2005. PMID: 16046522 Free PMC article.

3

Regulation of TNF-related apoptosis-inducing ligand on primary CD4+ T cells by HIV-1: role of type I IFN-producing plasmacytoid dendritic cells.

Herbeuval JP, Hardy AW, Boasso A, Anderson SA, Dolan MJ, Dy M, Shearer GM. Herbeuval JP, et al. Among authors: shearer gm. Proc Natl Acad Sci U S A. 2005 Sep 27;102(39):13974-9. doi: 10.1073/pnas.0505251102. Epub 2005 Sep 20. Proc Natl Acad Sci U S A. 2005. PMID: 16174727 Free PMC article.

4

Differential expression of IFN-alpha and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients.

Herbeuval JP, Nilsson J, Boasso A, Hardy AW, Kruhlak MJ, Anderson SA, Dolan MJ, Dy M, Andersson J, Shearer GM. Herbeuval JP, et al. Among authors: shearer gm. Proc Natl Acad Sci U S A. 2006 May 2;103(18):7000-5. doi: 10.1073/pnas.0600363103. Epub 2006 Apr 21. Proc Natl Acad Sci U S A. 2006. PMID: 16632604 Free PMC article.

5

HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells.

Boasso A, Herbeuval JP, Hardy AW, Anderson SA, Dolan MJ, Fuchs D, Shearer GM. Boasso A, et al. Among authors: shearer gm. Blood. 2007 Apr 15;109(8):3351-9. doi: 10.1182/blood-2006-07-034785. Epub 2006 Dec 7. Blood. 2007. PMID: 17158233 Free PMC article. Clinical Trial.

6

How does indoleamine 2,3-dioxygenase contribute to HIV-mediated immune dysregulation.

Boasso A, Shearer GM. Boasso A, et al. Among authors: shearer gm. Curr Drug Metab. 2007 Apr;8(3):217-23. doi: 10.2174/138920007780362527. Curr Drug Metab. 2007. PMID: 17430110 Review.

7

Chronic innate immune activation as a cause of HIV-1 immunopathogenesis.

Boasso A, Shearer GM. Boasso A, et al. Among authors: shearer gm. Clin Immunol. 2008 Mar;126(3):235-42. doi: 10.1016/j.clim.2007.08.015. Epub 2007 Oct 3. Clin Immunol. 2008. PMID: 17916442 Free PMC article. Review.

8

PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: restricted expression of type I interferon receptor by CCR5-expressing leukocytes.

Boasso A, Hardy AW, Landay AL, Martinson JL, Anderson SA, Dolan MJ, Clerici M, Shearer GM. Boasso A, et al. Among authors: shearer gm. Clin Immunol. 2008 Oct;129(1):132-44. doi: 10.1016/j.clim.2008.05.009. Epub 2008 Jul 22. Clin Immunol. 2008. PMID: 18650129 Free PMC article.

9

Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells.

Boasso A, Herbeuval JP, Hardy AW, Winkler C, Shearer GM. Boasso A, et al. Among authors: shearer gm. Blood. 2005 Feb 15;105(4):1574-81. doi: 10.1182/blood-2004-06-2089. Epub 2004 Oct 5. Blood. 2005. PMID: 15466932 Free article.

10

Restoration of HIV-specific cell-mediated immune responses by interleukin-12 in vitro.

Clerici M, Lucey DR, Berzofsky JA, Pinto LA, Wynn TA, Blatt SP, Dolan MJ, Hendrix CW, Wolf SF, Shearer GM. Clerici M, et al. Among authors: shearer gm. Science. 1993 Dec 10;262(5140):1721-4. doi: 10.1126/science.7903123. Science. 1993. PMID: 7903123

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