Pesu M - Search Results

1

T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.

Pesu M, Watford WT, Wei L, Xu L, Fuss I, Strober W, Andersson J, Shevach EM, Quezado M, Bouladoux N, Roebroek A, Belkaid Y, Creemers J, O'Shea JJ. Pesu M, et al. Nature. 2008 Sep 11;455(7210):246-50. doi: 10.1038/nature07210. Nature. 2008. PMID: 18701887 Free PMC article.

2

A new modality for immunosuppression: targeting the JAK/STAT pathway.

O'Shea JJ, Pesu M, Borie DC, Changelian PS. O'Shea JJ, et al. Among authors: pesu m. Nat Rev Drug Discov. 2004 Jul;3(7):555-64. doi: 10.1038/nrd1441. Nat Rev Drug Discov. 2004. PMID: 15232577 Review. No abstract available.

3

The Janus kinases (Jaks).

Yamaoka K, Saharinen P, Pesu M, Holt VE 3rd, Silvennoinen O, O'Shea JJ. Yamaoka K, et al. Among authors: pesu m. Genome Biol. 2004;5(12):253. doi: 10.1186/gb-2004-5-12-253. Epub 2004 Nov 30. Genome Biol. 2004. PMID: 15575979 Free PMC article. Review.

4

Jak3, severe combined immunodeficiency, and a new class of immunosuppressive drugs.

Pesu M, Candotti F, Husa M, Hofmann SR, Notarangelo LD, O'Shea JJ. Pesu M, et al. Immunol Rev. 2005 Feb;203:127-42. doi: 10.1111/j.0105-2896.2005.00220.x. Immunol Rev. 2005. PMID: 15661026 Review.

5

New strategies for immunosuppression: interfering with cytokines by targeting the Jak/Stat pathway.

O'Shea JJ, Park H, Pesu M, Borie D, Changelian P. O'Shea JJ, et al. Among authors: pesu m. Curr Opin Rheumatol. 2005 May;17(3):305-11. doi: 10.1097/01.bor.0000160781.07174.db. Curr Opin Rheumatol. 2005. PMID: 15838241 Review.

6

Identification of an acquired mutation in Jak2 provides molecular insights into the pathogenesis of myeloproliferative disorders.

Pesu M, O'Shea J, Hennighausen L, Silvennoinen O. Pesu M, et al. Mol Interv. 2005 Aug;5(4):211-5. doi: 10.1124/mi.5.4.4. Mol Interv. 2005. PMID: 16123535 No abstract available.

7

Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon gamma.

Pesu M, Muul L, Kanno Y, O'Shea JJ. Pesu M, et al. Blood. 2006 Aug 1;108(3):983-5. doi: 10.1182/blood-2005-09-3824. Epub 2006 Apr 20. Blood. 2006. PMID: 16627761 Free PMC article.

8

Therapeutic targeting of Janus kinases.

Pesu M, Laurence A, Kishore N, Zwillich SH, Chan G, O'Shea JJ. Pesu M, et al. Immunol Rev. 2008 Jun;223:132-42. doi: 10.1111/j.1600-065X.2008.00644.x. Immunol Rev. 2008. PMID: 18613833 Free PMC article. Review.

9

CD4+ FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner.

Andersson J, Tran DQ, Pesu M, Davidson TS, Ramsey H, O'Shea JJ, Shevach EM. Andersson J, et al. Among authors: pesu m. J Exp Med. 2008 Sep 1;205(9):1975-81. doi: 10.1084/jem.20080308. Epub 2008 Aug 18. J Exp Med. 2008. PMID: 18710931 Free PMC article.

10

Tpl2 kinase regulates T cell interferon-gamma production and host resistance to Toxoplasma gondii.

Watford WT, Hissong BD, Durant LR, Yamane H, Muul LM, Kanno Y, Tato CM, Ramos HL, Berger AE, Mielke L, Pesu M, Solomon B, Frucht DM, Paul WE, Sher A, Jankovic D, Tsichlis PN, O'Shea JJ. Watford WT, et al. Among authors: pesu m. J Exp Med. 2008 Nov 24;205(12):2803-12. doi: 10.1084/jem.20081461. Epub 2008 Nov 10. J Exp Med. 2008. PMID: 19001140 Free PMC article.

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