Handa S - Search Results

1

Hydrogen-rich pure water prevents superoxide formation in brain slices of vitamin C-depleted SMP30/GNL knockout mice.

Sato Y, Kajiyama S, Amano A, Kondo Y, Sasaki T, Handa S, Takahashi R, Fukui M, Hasegawa G, Nakamura N, Fujinawa H, Mori T, Ohta M, Obayashi H, Maruyama N, Ishigami A. Sato Y, et al. Among authors: handa s. Biochem Biophys Res Commun. 2008 Oct 24;375(3):346-50. doi: 10.1016/j.bbrc.2008.08.020. Epub 2008 Aug 14. Biochem Biophys Res Commun. 2008. PMID: 18706888

2

SMP30 deficiency in mice causes an accumulation of neutral lipids and phospholipids in the liver and shortens the life span.

Ishigami A, Kondo Y, Nanba R, Ohsawa T, Handa S, Kubo S, Akita M, Maruyama N. Ishigami A, et al. Among authors: handa s. Biochem Biophys Res Commun. 2004 Mar 12;315(3):575-80. doi: 10.1016/j.bbrc.2004.01.091. Biochem Biophys Res Commun. 2004. PMID: 14975739

3

Vitamin C is not essential for carnitine biosynthesis in vivo: verification in vitamin C-depleted senescence marker protein-30/gluconolactonase knockout mice.

Furusawa H, Sato Y, Tanaka Y, Inai Y, Amano A, Iwama M, Kondo Y, Handa S, Murata A, Nishikimi M, Goto S, Maruyama N, Takahashi R, Ishigami A. Furusawa H, et al. Among authors: handa s. Biol Pharm Bull. 2008 Sep;31(9):1673-9. doi: 10.1248/bpb.31.1673. Biol Pharm Bull. 2008. PMID: 18758058 Free article.

4

Vitamin C depletion increases superoxide generation in brains of SMP30/GNL knockout mice.

Kondo Y, Sasaki T, Sato Y, Amano A, Aizawa S, Iwama M, Handa S, Shimada N, Fukuda M, Akita M, Lee J, Jeong KS, Maruyama N, Ishigami A. Kondo Y, et al. Among authors: handa s. Biochem Biophys Res Commun. 2008 Dec 5;377(1):291-6. doi: 10.1016/j.bbrc.2008.09.132. Epub 2008 Oct 9. Biochem Biophys Res Commun. 2008. PMID: 18848523

5

Establishment and characterization of hepatocytes from an Immortomouse/SMP30/GNL knockout mouse hybrid lacking vitamin C to study vitamin C transport.

Amano A, Handa S, Aigaki T, Shigemoto K, Maruyama N, Ishigami A. Amano A, et al. Among authors: handa s. J Biochem. 2011 Dec;150(6):671-8. doi: 10.1093/jb/mvr109. Epub 2011 Sep 7. J Biochem. 2011. PMID: 21903636

6

Senescence marker protein-30 regulates Akt activity and contributes to cell survival in Hep G2 cells.

Matsuyama S, Kitamura T, Enomoto N, Fujita T, Ishigami A, Handa S, Maruyama N, Zheng D, Ikejima K, Takei Y, Sato N. Matsuyama S, et al. Among authors: handa s. Biochem Biophys Res Commun. 2004 Aug 20;321(2):386-90. doi: 10.1016/j.bbrc.2004.06.161. Biochem Biophys Res Commun. 2004. PMID: 15358188

7

Senescence marker protein-30 (SMP30) induces formation of microvilli and bile canaliculi in Hep G2 cells.

Ishigami A, Fujita T, Inoue H, Handa S, Kubo S, Kondo Y, Maruyama N. Ishigami A, et al. Among authors: handa s. Cell Tissue Res. 2005 May;320(2):243-9. doi: 10.1007/s00441-004-1073-5. Epub 2005 Feb 16. Cell Tissue Res. 2005. PMID: 15714273

8

Senescence marker protein 30 functions as gluconolactonase in L-ascorbic acid biosynthesis, and its knockout mice are prone to scurvy.

Kondo Y, Inai Y, Sato Y, Handa S, Kubo S, Shimokado K, Goto S, Nishikimi M, Maruyama N, Ishigami A. Kondo Y, et al. Among authors: handa s. Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5723-8. doi: 10.1073/pnas.0511225103. Epub 2006 Apr 3. Proc Natl Acad Sci U S A. 2006. PMID: 16585534 Free PMC article.

9

Over-expression of Senescence Marker Protein-30 decreases reactive oxygen species in human hepatic carcinoma Hep G2 cells.

Handa S, Maruyama N, Ishigami A. Handa S, et al. Biol Pharm Bull. 2009 Oct;32(10):1645-8. doi: 10.1248/bpb.32.1645. Biol Pharm Bull. 2009. PMID: 19801822 Free article.

10

Ascorbic acid prevents protein oxidation in livers of senescence marker protein-30/gluconolactonase knockout mice.

Sato Y, Amano A, Kishimoto Y, Takahashi K, Handa S, Maruyama N, Ishigami A. Sato Y, et al. Among authors: handa s. Geriatr Gerontol Int. 2014 Oct;14(4):989-95. doi: 10.1111/ggi.12162. Epub 2013 Oct 10. Geriatr Gerontol Int. 2014. PMID: 24118935

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