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Millepachine, a novel chalcone, induces G2/M arrest by inhibiting CDK1 activity and causing apoptosis via ROS-mitochondrial apoptotic pathway in human hepatocarcinoma cells in vitro and in vivo.
Wu W, Ye H, Wan L, Han X, Wang G, Hu J, Tang M, Duan X, Fan Y, He S, Huang L, Pei H, Wang X, Li X, Xie C, Zhang R, Yuan Z, Mao Y, Wei Y, Chen L. Wu W, et al. Carcinogenesis. 2013 Jul;34(7):1636-43. doi: 10.1093/carcin/bgt087. Epub 2013 Mar 7. Carcinogenesis. 2013. PMID: 23471882
PNAS-4, a novel pro-apoptotic gene, can potentiate antineoplastic effects of cisplatin.
Yuan Z, Yan F, Wang YS, Liu HY, Gou LT, Zhao XY, Lai ST, Deng HX, Li J, Ding ZY, Xiong SQ, Kan B, Mao YQ, Chen LJ, Wei YQ, Zhao X. Yuan Z, et al. Among authors: mao yq. Cancer Chemother Pharmacol. 2009 Dec;65(1):13-25. doi: 10.1007/s00280-009-0998-5. Epub 2009 Apr 22. Cancer Chemother Pharmacol. 2009. PMID: 19387645
192 results