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Outcomes following HSCT using fludarabine, busulfan, and thymoglobulin: a matched comparison to allogeneic transplants conditioned with busulfan and cyclophosphamide.
Bredeson CN, Zhang MJ, Agovi MA, Bacigalupo A, Bahlis NJ, Ballen K, Brown C, Chaudhry MA, Horowitz MM, Kurian S, Quinlan D, Muehlenbien CE, Russell JA, Savoie L, Rizzo JD, Stewart DA. Bredeson CN, et al. Among authors: brown c. Biol Blood Marrow Transplant. 2008 Sep;14(9):993-1003. doi: 10.1016/j.bbmt.2008.06.009. Biol Blood Marrow Transplant. 2008. PMID: 18721762 Free PMC article.
Allogeneic transplantation for adult acute leukemia in first and second remission with a novel regimen incorporating daily intravenous busulfan, fludarabine, 400 CGY total-body irradiation, and thymoglobulin.
Russell JA, Savoie ML, Balogh A, Turner AR, Larratt L, Chaudhry MA, Storek J, Bahlis NJ, Brown CB, Quinlan D, Geddes M, Stewart DA. Russell JA, et al. Biol Blood Marrow Transplant. 2007 Jul;13(7):814-21. doi: 10.1016/j.bbmt.2007.03.003. Epub 2007 Apr 23. Biol Blood Marrow Transplant. 2007. PMID: 17580259 Free article.
Transplantation from matched siblings using once-daily intravenous busulfan/fludarabine with thymoglobulin: a myeloablative regimen with low nonrelapse mortality in all but older patients with high-risk disease.
Russell JA, Duan Q, Chaudhry MA, Savoie ML, Balogh A, Turner AR, Larratt L, Storek J, Bahlis NJ, Brown CB, Quinlan D, Geddes M, Zacarias N, Daly A, Duggan P, Stewart DA. Russell JA, et al. Biol Blood Marrow Transplant. 2008 Aug;14(8):888-95. doi: 10.1016/j.bbmt.2008.05.010. Biol Blood Marrow Transplant. 2008. PMID: 18640572 Free article. Clinical Trial.
The addition of 400 cGY total body irradiation to a regimen incorporating once-daily intravenous busulfan, fludarabine, and antithymocyte globulin reduces relapse without affecting nonrelapse mortality in acute myelogenous leukemia.
Russell JA, Irish W, Balogh A, Chaudhry MA, Savoie ML, Turner AR, Larratt L, Storek J, Bahlis NJ, Brown CB, Quinlan D, Geddes M, Zacarias N, Daly A, Duggan P, Stewart DA. Russell JA, et al. Biol Blood Marrow Transplant. 2010 Apr;16(4):509-14. doi: 10.1016/j.bbmt.2009.11.017. Epub 2009 Dec 3. Biol Blood Marrow Transplant. 2010. PMID: 19948235 Free article.
Development and validation of a test dose strategy for once-daily i.v. busulfan: importance of fixed infusion rate dosing.
Kangarloo SB, Naveed F, Ng ES, Chaudhry MA, Wu J, Bahlis NJ, Brown CB, Daly A, Duggan P, Geddes M, Quinlan D, Savoie ML, Shafey M, Stewart DA, Storek J, Yang M, Zacarias N, Yue P, Magliocco AM, Russell JA. Kangarloo SB, et al. Biol Blood Marrow Transplant. 2012 Feb;18(2):295-301. doi: 10.1016/j.bbmt.2011.07.015. Epub 2011 Jul 27. Biol Blood Marrow Transplant. 2012. PMID: 21801704 Free article. Clinical Trial.
Establishing a target exposure for once-daily intravenous busulfan given with fludarabine and thymoglobulin before allogeneic transplantation.
Russell JA, Kangarloo SB, Williamson T, Chaudhry MA, Savoie ML, Turner AR, Larratt L, Storek J, Bahlis NJ, Shafey M, Brown CB, Yang M, Geddes M, Zacarias N, Yue P, Duggan P, Stewart DA, Daly A. Russell JA, et al. Biol Blood Marrow Transplant. 2013 Sep;19(9):1381-6. doi: 10.1016/j.bbmt.2013.07.002. Epub 2013 Jul 17. Biol Blood Marrow Transplant. 2013. PMID: 23871781 Free article.
Adult recipients of matched related donor blood cell transplants given myeloablative regimens including pretransplant antithymocyte globulin have lower mortality related to graft-versus-host disease: a matched pair analysis.
Russell JA, Turner AR, Larratt L, Chaudhry A, Morris D, Brown C, Quinlan D, Stewart D. Russell JA, et al. Among authors: brown c. Biol Blood Marrow Transplant. 2007 Mar;13(3):299-306. doi: 10.1016/j.bbmt.2006.10.017. Biol Blood Marrow Transplant. 2007. PMID: 17317583 Free article. Clinical Trial.
High busulfan exposure is associated with worse outcomes in a daily i.v. busulfan and fludarabine allogeneic transplant regimen.
Geddes M, Kangarloo SB, Naveed F, Quinlan D, Chaudhry MA, Stewart D, Savoie ML, Bahlis NJ, Brown C, Storek J, Andersson BS, Russell JA. Geddes M, et al. Among authors: brown c. Biol Blood Marrow Transplant. 2008 Feb;14(2):220-8. doi: 10.1016/j.bbmt.2007.10.028. Biol Blood Marrow Transplant. 2008. PMID: 18215782 Free article. Clinical Trial.
Fludarabine, busulfan, antithymocyte globulin, and total body irradiation for pretransplantation conditioning in acute lymphoblastic leukemia: excellent outcomes in all but older patients with comorbidities.
Daly A, Savoie ML, Geddes M, Chaudhry A, Stewart D, Duggan P, Bahlis N, Storek J, Brown C, Shafey M, Turner AR, Russell J. Daly A, et al. Among authors: brown c. Biol Blood Marrow Transplant. 2012 Dec;18(12):1921-6. doi: 10.1016/j.bbmt.2012.07.017. Epub 2012 Jul 27. Biol Blood Marrow Transplant. 2012. PMID: 22842330 Free article.
Influence of comorbidities on transplant outcomes in patients aged 50 years or more after myeloablative conditioning incorporating fludarabine, BU and ATG.
El Kourashy S, Williamson T, Chaudhry MA, Savoie ML, Turner AR, Larratt L, Storek J, Bahlis NJ, Brown CB, Yang M, Quinlan D, Geddes M, Zacarias N, Daly A, Duggan P, Stewart DA, Russell JA. El Kourashy S, et al. Among authors: brown cb. Bone Marrow Transplant. 2011 Aug;46(8):1077-83. doi: 10.1038/bmt.2010.257. Epub 2010 Nov 8. Bone Marrow Transplant. 2011. PMID: 21057555
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