Kwiatkowski DJ - Search Results

1

An efficient and versatile system for acute and chronic modulation of renal tubular function in transgenic mice.

Traykova-Brauch M, Schönig K, Greiner O, Miloud T, Jauch A, Bode M, Felsher DW, Glick AB, Kwiatkowski DJ, Bujard H, Horst J, von Knebel Doeberitz M, Niggli FK, Kriz W, Gröne HJ, Koesters R. Traykova-Brauch M, et al. Among authors: kwiatkowski dj. Nat Med. 2008 Sep;14(9):979-84. doi: 10.1038/nm.1865. Nat Med. 2008. PMID: 18724376 Free PMC article.

2

Tuberous sclerosis complex 1: an epithelial tumor suppressor essential to prevent spontaneous prostate cancer in aged mice.

Kladney RD, Cardiff RD, Kwiatkowski DJ, Chiang GG, Weber JD, Arbeit JM, Lu ZH. Kladney RD, et al. Among authors: kwiatkowski dj. Cancer Res. 2010 Nov 1;70(21):8937-47. doi: 10.1158/0008-5472.CAN-10-1646. Epub 2010 Oct 12. Cancer Res. 2010. PMID: 20940396 Free PMC article.

3

Equivalent benefit of mTORC1 blockade and combined PI3K-mTOR blockade in a mouse model of tuberous sclerosis.

Pollizzi K, Malinowska-Kolodziej I, Stumm M, Lane H, Kwiatkowski D. Pollizzi K, et al. Mol Cancer. 2009 Jun 15;8:38. doi: 10.1186/1476-4598-8-38. Mol Cancer. 2009. PMID: 19527517 Free PMC article.

4

Comprehensive molecular characterization of urothelial bladder carcinoma.

Cancer Genome Atlas Research Network. Cancer Genome Atlas Research Network. Nature. 2014 Mar 20;507(7492):315-22. doi: 10.1038/nature12965. Epub 2014 Jan 29. Nature. 2014. PMID: 24476821 Free PMC article.

5

Critical role for hypothalamic mTOR activity in energy balance.

Mori H, Inoki K, Münzberg H, Opland D, Faouzi M, Villanueva EC, Ikenoue T, Kwiatkowski D, MacDougald OA, Myers MG Jr, Guan KL. Mori H, et al. Cell Metab. 2009 Apr;9(4):362-74. doi: 10.1016/j.cmet.2009.03.005. Cell Metab. 2009. PMID: 19356717 Free PMC article.

6

AMP-activated protein kinase signaling results in cytoplasmic sequestration of p27.

Short JD, Houston KD, Dere R, Cai SL, Kim J, Johnson CL, Broaddus RR, Shen J, Miyamoto S, Tamanoi F, Kwiatkowski D, Mills GB, Walker CL. Short JD, et al. Cancer Res. 2008 Aug 15;68(16):6496-506. doi: 10.1158/0008-5472.CAN-07-5756. Cancer Res. 2008. PMID: 18701472 Free PMC article.

7

Critical roles for the TSC-mTOR pathway in β-cell function.

Mori H, Inoki K, Opland D, Münzberg H, Villanueva EC, Faouzi M, Ikenoue T, Kwiatkowski DJ, Macdougald OA, Myers MG Jr, Guan KL. Mori H, et al. Among authors: kwiatkowski dj. Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1013-22. doi: 10.1152/ajpendo.00262.2009. Epub 2009 Aug 18. Am J Physiol Endocrinol Metab. 2009. PMID: 19690069 Free PMC article.

8

Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition.

Breuleux M, Klopfenstein M, Stephan C, Doughty CA, Barys L, Maira SM, Kwiatkowski D, Lane HA. Breuleux M, et al. Mol Cancer Ther. 2009 Apr;8(4):742-53. doi: 10.1158/1535-7163.MCT-08-0668. Mol Cancer Ther. 2009. PMID: 19372546 Free PMC article.

9

Gelsolin deficiency blocks podosome assembly and produces increased bone mass and strength.

Chellaiah M, Kizer N, Silva M, Alvarez U, Kwiatkowski D, Hruska KA. Chellaiah M, et al. J Cell Biol. 2000 Feb 21;148(4):665-78. doi: 10.1083/jcb.148.4.665. J Cell Biol. 2000. PMID: 10684249 Free PMC article.

10

Comprehensive genomic characterization of squamous cell lung cancers.

Cancer Genome Atlas Research Network. Cancer Genome Atlas Research Network. Nature. 2012 Sep 27;489(7417):519-25. doi: 10.1038/nature11404. Epub 2012 Sep 9. Nature. 2012. PMID: 22960745 Free PMC article.

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